Full Name
Joanna Maria Brzostek
(not current staff)
Main Affiliation


Results 1-18 of 18 (Search time: 0.027 seconds).

Issue DateTitleAuthor(s)
12019A Dual Inhibitor of Cdc7/Cdk9 Potently Suppresses T Cell ActivationChen, E.W. ; Tay, N.Q. ; Brzostek, J. ; Gascoigne, N.R.J. ; Rybakin, V. 
221-Feb-2023CD28-CAR-T cell activation through FYN kinase signaling rather than LCK enhances therapeutic performanceWu, Ling; Brzostek, Joanna ; Vale, Previtha Dawn Sakthi ; Wei, Qianru ; Koh, Clara KT ; Ong, June Xu Hui ; Wu, Liang-zhe ; Tan, Jia Chi; Chua, Yen Leong ; Yap, Jiawei ; Song, Yuan ; Tan, Vivian Jia Yi ; Tan, Triscilla YY; Lai, Junyun ; MacAry, Paul A ; Gascoigne, Nicholas RJ 
32016Cell type-specific regulation of immunological synapse dynamics by B7 ligand recognitionBrzostek, J ; Gascoigne, N.R.J ; Rybakin, V 
42018Development of a screening strategy for new modulators of T cell receptor signaling and T cell activationChen E.W.; Brzostek J. ; Gascoigne N.R.J. ; Rybakin V. 
529-Oct-2021Editorial: Vibrio Virulence Regulation and Host InteractionsHuang, Lixing; Fu, Yang; Sun, Wenxiang; Brzostek, Joanna 
67-Apr-2021Expansion of an Unusual Virtual Memory CD8+ Subpopulation Bearing V?3.2 TCR in Themis-Deficient MicePrasad, Mukul ; Wojciech, Lukasz ; Brzostek, Joanna ; Hu, Jianfang; Chua, Yen Leong ; Tung, Desmond Wai Hon ; Yap, Jiawei ; Rybakin, Vasily ; Gascoigne, Nicholas R. J. 
72015Identification of a novel lymphoid population in the murine epidermisAlmeida, F.F; Tenno, M; Brzostek, J ; Li, J.L; Allies, G; Hoeffel, G; See, P; Ng, L.G ; Fehling, H.J; Gascoigne, N.R.J ; Taniuchi, I; Ginhoux, F 
87-Jul-2020Lck bound to coreceptor is less active than free LckWei, Qianru ; Brzostek, Joanna ; Sankaran, Shvetha ; Casas, Javier ; Hew, Lois Shi-Qi; Yap, Jiawei ; Zhao, Xiang ; Wojciech, Lukasz ; Gascoigne, Nicholas RJ 
92010Matched sizes of activating and inhibitory receptor ligand pairs are required for optimal signal integration by human natural killer cellsKöhler K.; Xiong S.; Brzostek J. ; Mehrabi M.; Eissmann P.; Harrison A.; Cordoba S.-P.; Oddos S.; Miloserdov V.; Gould K.; Burroughs N.J.; van der Merwe P.A.; Davis D.M.
102010Modification of the Campylobacter jejuni flagellin glycan by the product of the Cj1295 homopolymeric-tract-containing geneHitchen, P; Brzostek, J ; Panico, M; Butler, J.A; Morris, H.R; Dell, A; Linton, D
1111-Oct-2021Non-Stimulatory pMHC Enhance CD8 T Cell Effector Functions by Recruiting Coreceptor-Bound LckZhao, Xiang ; Wu, Liang-Zhe ; Ng, Esther K. Y. ; Leow, Kerisa W. S.; Wei, Qianru ; Gascoigne, Nicholas R. J. ; Brzostek, Joanna 
122018Nonstimulatory peptide-MHC enhances human T-cell antigen-specific responses by amplifying proximal TCR signalingZhao X. ; Sankaran S. ; Yap J. ; Too C.T. ; Ho Z.Z. ; Dolton G.; Legut M.; Ren E.C. ; Sewell A.K.; Bertoletti A. ; MacAry P.A. ; Brzostek J. ; Gascoigne N.R.J. 
134-Aug-2021Single Molecule Force Spectroscopy Reveals Distinctions in Key Biophysical Parameters of alpha beta T-Cell Receptors Compared with Chimeric Antigen Receptors Directed at the Same LigandBanik, Debasis; Hamidinia, Maryam; Brzostek, Joanna ; Wu, Ling; Stephens, Hannah M; MacAry, Paul A; Reinherz, Ellis L; Gascoigne, Nicholas RJ ; Lang, Matthew J
1418-Feb-2021Targeting car to the peptide?mhc complex reveals distinct signaling compared to that of tcr in a jurkat t cell modelWu, Ling; Brzostek, Joanna ; Sankaran, Shvetha ; Wei, Qianru ; Yap, Jiawei ; Tan, Triscilla Y. Y.; Lai, Junyun ; Macary, Paul A. ; Gascoigne, Nicholas R. J. 
151-May-2018Themis integrates signalling from self pMHC and cytokines in mature CD8+T cellsGascoigne, Nicholas RJ ; Zhao, Xiang ; Mehta, Monika ; Gautam, Namrata; Brzostek, Joanna 
1611-Nov-2020Themis regulates metabolic signaling and effector functions in CD4+ T cells by controlling NFAT nuclear translocationPrasad, Mukul ; Brzostek, Joanna ; Gautam, Namrata ; Balyan, Renu ; Rybakin, Vasily ; Gascoigne, Nicholas R. J. 
1727-Nov-2018Themis-associated phosphatase activity controls signaling in T cell developmentMehta, Monika; Brzostek, Joanna ; Chen, Elijah W ; Tung, Desmond WH ; Chen, Shuting; Sankaran, Shvetha; Yap, Jiawei ; Rybakin, Vasily ; Gascoigne, Nicholas RJ 
181-May-2022Utilizing distinct CAR and TCR signaling to generate enhanced cellular immunotherapyGascoigne, Nicholas RJ ; Wu, Ling ; Brzostek, Joanna ; Wei, Qianru ; Vale, Previtha Dawn Sakthi ; Koh, Clara KT ; Chua, Yen Long; Yap, Jiawei ; Tan, Triscilla YY; Lai, Junyun ; MacAry, Paul A