Nicholas Robert John Gascoigne


Full Name
Nicholas Robert John Gascoigne
Gascoigne, Nicholas R J
Gascoigne N.R.J
Gascoigne, Nicholas Robert John
Main Affiliation


Results 1-20 of 36 (Search time: 0.012 seconds).

Issue DateTitleAuthor(s)
12019A Dual Inhibitor of Cdc7/Cdk9 Potently Suppresses T Cell ActivationChen, E.W. ; Tay, N.Q. ; Brzostek, J. ; Gascoigne, N.R.J. ; Rybakin, V. 
22015A THEMIS:SHP1 complex promotes T-cell survivalPaster W.; Bruger A.M.; Katsch K.; Gregoire C.; Roncagalli R.; Fu G.; Gascoigne, Nicholas Robert John ; Cohnen A.; Feller S.M.; Simister P.C.; Molder K.C.; Cordoba S.-P.; Dushek O.; Malissen B.; Acuto O.
32014Allelic exclusion of TCR �-chains upon severe restriction of V� repertoireRybakin V.; Westernberg L.; Fu G.; Kim H.-O.; Ampudia J.; Sauer K.; Gascoigne N.R.J. 
421-Feb-2023CD28-CAR-T cell activation through FYN kinase signaling rather than LCK enhances therapeutic performanceWu, Ling; Brzostek, Joanna ; Vale, Previtha Dawn Sakthi ; Wei, Qianru ; Koh, Clara KT ; Ong, June Xu Hui ; Wu, Liang-zhe ; Tan, Jia Chi; Chua, Yen Leong ; Yap, Jiawei ; Song, Yuan ; Tan, Vivian Jia Yi ; Tan, Triscilla YY; Lai, Junyun ; MacAry, Paul A ; Gascoigne, Nicholas RJ 
52017CD40L expression allows CD8+ T cells to promote their own expansion and differentiation through dendritic cellsTay, N.Q ; Lee, D.C.P ; Chua, Y.L ; Prabhu, N ; Gascoigne, N.R.J ; Kemeny, D.M 
62016Cell type-specific regulation of immunological synapse dynamics by B7 ligand recognitionBrzostek, J ; Gascoigne, N.R.J ; Rybakin, V 
71-Jan-2023Colonization with two different Blastocystis subtypes in DSS-induced colitis mice is associated with strikingly different microbiome and pathological featuresDeng, Lei; Wojciech, Lukasz ; Png, Chin Wen ; Kioh, Dorinda Yan Qin ; Gu, Yuxiang; Aung, Thet Tun ; Malleret, Benoit ; Chan, Eric Chun Yong ; Peng, Guangneng; Zhang, Yongliang ; Gascoigne, Nicholas Robert John ; Tan, Kevin Shyong Wei 
8-Colonization with ubiquitous protist Blastocystis ST1 ameliorates DSS-induced colitis and promotes beneficial microbiota and immune outcomesDeng, Lei ; Wojciech, Lukasz ; Png, Chin Wen ; Kioh, Yan Qin Dorinda ; Ng, Geok Choo ; Chan, Eric Chun Yong ; Zhang, Yongliang ; Gascoigne, Nicholas RJ ; Tan, Kevin Shyong Wei 
921-Feb-2019Defining the structural basis for human alloantibody binding to human leukocyte antigen allele HLA-A(star)11:01Gu, Yue ; Wong, Yee Hwa; Liew, Chong Wai; Chan, Conrad EZ; Murali, Tanusya M ; Yap, Jiawei; Too, Chien Tei ; Purushotorman, Kiren; Hamidinia, Maryam; El Sahili, Abbas; Goh, Angeline TH; Teo, Rachel ZC; Wood, Kathryn J; Hanson, Brendon J; Gascoigne, Nicholas RJ ; Lescar, Julien; Vathsala, Anantharaman ; MacAry, Paul A 
102020Defining the structural basis for human leukocyte antigen reactivity in clinical transplantationGu, Y.; Koh, R.W.K.; Lai, M.L.; Pochinco, D.; Teo, R.Z.C.; Chan, M.; Murali, T.M. ; Liew, C.W.; Wong, Y.H.; Gascoigne, N.R.J. ; Wood, K.J.; Lescar, J.; Nickerson, P.; MacAry, P.A. ; Vathsala, A. 
112018Development of a screening strategy for new modulators of T cell receptor signaling and T cell activationChen E.W.; Brzostek J. ; Gascoigne N.R.J. ; Rybakin V. 
1216-Apr-2021DUSP16 promotes cancer chemoresistance through regulation of mitochondria-mediated cell deathLow, Heng Boon ; Wong, Zhen Lim; Wu, Bangyuan; Kong, Li Ren ; Png, Chin Wen ; Cho, Yik-Lam; Li, Chun-Wei; Xiao, Fengchun; Xin, Xuan; Yang, Henry ; Loo, Jia Min; Lee, Fiona Yi Xin; Tan, Iain Bee Huat ; DasGupta, Ramanuj; Shen, Han-Ming; Schwarz, Herbert; Gascoigne, Nicholas RJ ; Goh, Boon Cher ; Xu, Xiaohong; Zhang, Yongliang 
132014Erratum: In silico modeling of itk activation kinetics in thymocytes suggests competing positive and negative IP 4 mediated feedbacks increase robustness (PLoS ONE (2014) 9:1)Mukherjee S.; Rigaud S.; Seok S.-C.; Fu G.; Prochenka A.; Dworkin M.; Gascoigne N.R.J. ; Vieland V.J.; Sauer K.; Das J.
147-Apr-2021Expansion of an Unusual Virtual Memory CD8+ Subpopulation Bearing V?3.2 TCR in Themis-Deficient MicePrasad, Mukul ; Wojciech, Lukasz ; Brzostek, Joanna ; Hu, Jianfang; Chua, Yen Leong ; Tung, Desmond Wai Hon ; Yap, Jiawei ; Rybakin, Vasily ; Gascoigne, Nicholas R. J. 
1518-Apr-2022Experimental colonization with Blastocystis ST4 is associated with protective immune responses and modulation of gut microbiome in a DSS-induced colitis mouse modelDeng, Lei; Wojciech, Lukasz ; Png, Chin Wen ; Koh, Eileen Yiling ; Aung, Thet Tun ; Kioh, Dorinda Yan Qin ; Chan, Eric Chun Yong ; Malleret, Benoit ; Zhang, Yongliang ; Peng, Guangneng; Gascoigne, Nicholas Robert John ; Tan, Kevin Shyong Wei 
162015Identification of a novel lymphoid population in the murine epidermisAlmeida, F.F; Tenno, M; Brzostek, J ; Li, J.L; Allies, G; Hoeffel, G; See, P; Ng, L.G ; Fehling, H.J; Gascoigne, N.R.J ; Taniuchi, I; Ginhoux, F 
172013In Silico Modeling of Itk Activation Kinetics in Thymocytes Suggests Competing Positive and Negative IP4 Mediated Feedbacks Increase RobustnessMukherjee S.; Rigaud S.; Seok S.-C.; Fu G.; Prochenka A.; Dworkin M.; Gascoigne N.R.J. ; Vieland V.J.; Sauer K.; Das J.
187-Jul-2020Lck bound to coreceptor is less active than free LckWei, Qianru ; Brzostek, Joanna ; Sankaran, Shvetha ; Casas, Javier ; Hew, Lois Shi-Qi; Yap, Jiawei ; Zhao, Xiang ; Wojciech, Lukasz ; Gascoigne, Nicholas RJ 
191-May-2017Molecular engineering of a therapeutic antibody for Blo t 5-induced allergic asthmaChan, JH Sherlynn ; Chua, Yen Leong ; Peh, Hong Yong ; Jovanovic, Vojislav ; Gascoigne, Nicholas RJ ; Wong, WS Fred ; Chew, Fook Tim ; Hanson, Brendon J ; Kemeny, David M ; MacAry, Paul A 
202012Negative selection assay based on stimulation of T cell receptor transgenic thymocytes with peptide-MHC tetramersRybakin V.; Gascoigne N.R.J.