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Tuan Zea Tan

rp01843

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Full Name
Tuan Zea Tan
Variants
Tan, T.Z.
Tan, Tuan Zea
 
Main Affiliation
 
Faculty
 
Email
csittz@nus.edu.sg
 

Publications

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Department:  DEAN'S OFFICE (MEDICINE)
Type:  Article
Department:  MEDICINE

Results 1-19 of 19 (Search time: 0.021 seconds).

Issue DateTitleAuthor(s)
12018A loss-of-function genetic screening reveals synergistic targeting of AKT/mTOR and WTN/β-catenin pathways for treatment of AML with high PRL-3 phosphataseZhou, J ; Toh, S.H.-M; Chan, Z.-L; Quah, J.Y; Chooi, J.-Y ; Tan, T.Z ; Chong, P.S.Y ; Zeng, Q ; Chng, W.-J 
21-Sep-2020ASLAN003, a potent dihydroorotate dehydrogenase inhibitor for differentiation of acute myeloid leukemia.Zhou, Jianbiao ; Yiying Quah, Jessie ; Ng, Yvonne ; Chooi, Jing-Yuan ; Hui-Min Toh, Sabrina ; Lin, Baohong; Zea Tan, Tuan ; Hosoi, Hiroki ; Osato, Motomi ; Seet, Qihui; Ooi, Lisa AG; Lindmark, Bertil; McHale, Mark; Chng, Wee-Joo 
3Jul-2017Belinostat exerts antitumor cytotoxicity through the ubiquitin-proteasome pathway in lung squamous cell carcinomaKong, L.R ; Tan, T.Z ; Ong, W.R; Bi, C; Huynh, H ; Lee, S.C ; Chng, W.J ; Eichhorn, P.J.A ; Goh, B.C 
411-Jul-2018BET Bromodomain inhibition promotes De-repression of TXNIP and activation of ASK1-MAPK pathway in acute myeloid leukemiaZhou Y.; Zhou J. ; Lu X.; Tan T.-Z. ; Chng W.-J. 
527-Sep-2021Epigenetic derepression converts PPAR gamma into a druggable target in triple-negative and endocrine-resistant breast cancersLoo, Ser Yue; Syn, Nicholas L; Koh, Angele Pei-Fern ; Teng, Janet Cheng-Fei ; Deivasigamani, Amudha; Tan, Tuan Zea ; Thike, Aye Aye ; Vali, Shireen ; Kapoor, Shweta; Wang, Xiaoyuan ; Wang, Jiong Wei ; Tan, Puay Hoon ; Yip, George W ; Sethi, Gautam ; Huang, Ruby Yun-Ju ; Hui, Kam Man ; Wang, Lingzhi ; Goh, Boon Cher ; Kumar, Alan Prem 
615-Sep-2019IL6 Promotes a STAT3-PRL3 Feedforward Loop via SHP2 Repression in Multiple MyelomaChong, Phyllis SY ; Zhou, Jianbiao ; Lim, Julia SL ; Hee, Yan Ting; Chooi, Jing-Yuan ; Chung, Tae-Hoon ; Tan, Zea Tuan ; Zeng, Qi ; Waller, Daniel D; Sebag, Michael; Chng, Wee-Joo 
72017Inhibition of LIN28B impairs leukemia cell growth and metabolism in acute myeloid leukemiaZhou, J ; Bi, C; Ching, Y.Q ; Chooi, J.-Y ; Lu, X; Quah, J.Y ; Toh, S.H.-M ; Chan, Z.-L; Tan, T.Z ; Chong, P.S ; Chng, W.-J 
81-Mar-2017LIN28B Activation by PRL-3 Promotes Leukemogenesis and a Stem Cell-like Transcriptional Program in AMLZhou, Jianbiao ; Chan, Zit-Liang; Bi, Chonglei; Lu, Xiao; Chong, Phyllis SY ; Chooi, Jing-Yuan ; Cheong, Lip-Lee; Liu, Shaw-Cheng; Ching, Ying Qing ; Zhou, Yafeng; Osato, Motomi; Tan, Tuan Zea ; Ng, Chin Hin ; Ng, Siok-Bian ; Wang, Shi ; Zeng, Qi ; Chng, Wee-Joo 
920-Aug-2016Manganese Superoxide Dismutase Expression Regulates the Switch Between an Epithelial and a Mesenchymal-Like Phenotype in Breast CarcinomaLoo, Ser Yue ; Hirpara, Jayshree L ; Pandey, Vijay ; Tan, Tuan Zea ; Yap, Celestial T ; Lobie, Peter E ; Thiery, Jean Paul ; Goh, Boon Cher ; Pervaiz, Shazib ; Clement, Marie-Veronique ; Kumar, Alan Prem 
101-Jan-2021MicroRNA-196a promotes renal cancer cell migration and invasion by targeting BRAM1 to regulate SMAD and MAPK signaling pathwaysCui, Jianzhou ; Yuan, Yi; Shanmugam, Muthu K ; Anbalagan, Durkeshwari; Tan, Tuan Zea ; Sethi, Gautam ; Kumar, Alan Prem ; Lim, Lina HK 
1126-Apr-2018NF-kappa B promotes the stem-like properties of leukemia cells by activation of LIN28BZhou, Jianbiao ; Chooi, Jing-Yuan ; Ching, Ying Qing ; Quah, Jessie Yiying ; Toh, Sabrina Hui-Min ; Ng, Yvonne ; Tan, Tuan Zea ; Chng, Wee-Joo 
1228-Feb-2019Non-canonical activation of beta-catenin by PRL-3 phosphatase in acute myeloid leukemiaChong, Phyllis SY ; Zhou, Jianbiao ; Chooi, Jing-Yuan ; Chan, Zit-Liang; Toh, Sabrina Hui Min ; Tan, Tuan Zea ; Wee, Sheena; Gunaratne, Jayantha ; Zeng, Qi ; Chng, Wee-Joo 
13Nov-2017PPARγ Ligand-induced Annexin A1 Expression Determines Chemotherapy Response via Deubiquitination of Death Domain Kinase RIP in Triple-negative Breast Cancers.Chen, Luxi ; Yuan, Yi; Kar, Shreya; Kanchi, Madhu M ; Arora, Suruchi; Kim, Ji E; Koh, Pei F ; Yousef, Einas; Samy, Ramar P ; Shanmugam, Muthu K ; Tuan Z ; Shin, Sung W; Arfuso, Frank; Shen, Han M ; Yang, Henry; Goh, Boon C ; Park, Joo I; Gaboury, Louis; Lobie, Peter E ; Sethi, Gautam ; Lim, Lina HK ; Kumar, Alan P 
142018RUNX1 and RUNX3 protect against YAP-mediated EMT, stemness and shorter survival outcomes in breast cancerKulkarni, M ; Tan, T.Z ; Sulaiman, N.B.s; Lamar, J.M; Bansal, P; Cui, J ; Qiao, Y ; Ito, Y 
151-May-2021SMARCA2 Is a Novel Interactor of NSD2 and Regulates Prometastatic PTP4A3 through Chromatin Remodeling in t(4;14) Multiple MyelomaChong, Phyllis SY ; Chooi, Jing Yuan; Lim, Julia SL ; Toh, Sabrina Hui Min ; Tan, Tuan Zea ; Chng, Wee-Joo 
162014SPHK1 regulates proliferation and survival responses in triplenegative breast cancerDatta, A ; Loo, S.Y ; Huang, B ; Wong, L ; Tan, S.S.L ; Tan, T.Z ; Lee, S.-C ; Thiery, J.P ; Lim, Y.C ; Yong, W.P ; Lam, Y ; Kumar, A.P ; Yap, C.T 
1729-Apr-2020Targeting codon 158 p53-mutant cancers via the induction of p53 acetylationKong, Li Ren ; Ong, Richard Weijie; Tan, Tuan Zea ; Salleh, Nur Afiqah Binte Mohamed ; Thangavelu, Matan; Chan, Jane Vin; Koh, Lie Yong Judice; Periyasamy, Giridharan; Lau, Jieying Amelia ; Le, Thi Bich Uyen; Wang, Lingzhi ; Lee, Miyoung; Kannan, Srinivasaraghavan; Verma, Chandra S ; Lim, Chwee Ming ; Chng, Wee Joo ; Lane, David P ; Venkitaraman, Ashok ; Hung, Huynh The; Cheok, Chit Fang ; Goh, Boon Cher 
182020Whole exome sequencing of multi-regional biopsies from metastatic lesions to evaluate actionable truncal mutations using a single-pass percutaneous techniqueHeong V.; Tay D.; Goh S.E. ; Wee B. ; Tan T.Z. ; Soo R. ; Pang B. ; Lim D. ; Gopinathan A. ; Ow S. ; Chee C.E. ; Goh B.C. ; Lee S.C. ; Yong W.P. ; Wong A. ; Omar M.F.M. ; Soong R. ; Tan D.S.P. 
192018X-linked inhibitor of apoptosis inhibition sensitizes acute myeloid leukemia cell response to TRAIL and chemotherapy through potentiated induction of proapoptotic machineryZhou, J. ; Lu, X.; Tan, T.Z. ; Chng, W.-J.