Full Name
Sir David Lane
Main Affiliation
 
 
Email
mdcsdl@nus.edu.sg
 

Publications

Results 1-9 of 9 (Search time: 0.022 seconds).

Issue DateTitleAuthor(s)
12017A yeast two-hybrid system for the screening and characterization of small-molecule inhibitors of protein-protein interactions identifies a novel putative Mdm2-binding site in p53Wong, J.H; Alfatah, M; Sin, M.F; Sim, H.M ; Verma, C.S ; Lane, D.P ; Arumugam, P 
22015Assessing the Efficacy of Mdm2/Mdm4-Inhibiting Stapled Peptides Using Cellular Thermal Shift AssaysXiong Tan, B; Brown, C.J; Ferrer, F.J; Yuen, T.Y; Quah, S.T; Chan, B.H; Jansson, A.E; Teo, H.L; Nordlund, P; Lane, D.P 
32016Avoiding drug resistance through extended drug target interfaces: A case for stapled peptidesWei, S.J; Chee, S; Yurlova, L; Lane, D ; Verma, C ; Brown, C; Ghadessy, F
42017Enhancing specific disruption of intracellular protein complexes by hydrocarbon stapled peptides using lipid based deliveryThean, D; Ebo, J.S; Luxton, T; Lee, X.C; Yuen, T.Y; Ferrer, F.J; Johannes, C.W; Lane, D.P ; Brown, C.J
52014High Mdm4 levels suppress p53 activity and enhance its half-life in acute myeloid leukaemiaTan, B.X; Khoo, K.H; Lim, T.M ; Lane, D.P 
62008MDM2 SNP309 is associated with high grade node positive breast tumours and is in linkage disequilibrium with a novel MDM2 intron 1 polymorphismPaulin, F.E.M; O'Neill, M; McGregor, G; Cassidy, A; Ashfield, A; Ali, C.W; Munro, A.J; Baker, L; Purdie, C.A; Lane, D.P ; Thompson, A.M
73-Dec-2009Modulation of p53 binding to MDM2: Computational studies reveal important roles of Tyr100Dastidar, S.G.; Lane, D.P. ; Verma, C.S. 
82011Mutant p53 uses p63 as a molecular chaperone to alter gene expression and induce a pro-invasive secretomeNeilsen, P.M; Noll, J.E; Suetani, R.J; Schulz, R.B; Al-Ejeh, F; Evdokiou, A; Lane, D.P ; Callen, D.F
92017The hot-spot p53R172H mutant promotes formation of giant spermatogonia triggered by DNA damageXue, Y; Raharja, A; Sim, W; Wong, E.S.M; Rahmat, S.A.B; Lane, D.P