Full Name
Hirpara J Laljibhai
Hirpara, J.L.
Hirpara, Jayshree L.
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Results 1-20 of 24 (Search time: 0.01 seconds).

Issue DateTitleAuthor(s)
125-Feb-2024A novel MTORC2-AKT-ROS axis triggers mitofission and mitophagy-associated execution of colorectal cancer cells upon drug-induced activation of mutant KRASKartini Iskandar ; Jonathan Foo ; Angeline Qiu Xia Liew ; Haiyuxin Zhu; Deepika Raman ; Jayshree L. Hirpara ; Yan Yi Leong; Maria V. Babak ; Anna A. Kirsanova; Anne-Sophie Armand; Franck Oury; Gregory Bellot ; Shazib Pervaiz 
22016Aberrant localization of apoptosis protease activating factor-1 in lipid raft sub-domains of diffuse large B cell lymphomasHirpara, J.L ; Loh, T ; Ng, S.B ; Chng, W.J ; Pervaiz, S 
32015Activation of surrogate death receptor signaling triggers peroxynitrite-dependent execution of cisplatinresistant cancer cellsSeah, S ; Low, I ; Hirpara, J.L ; Sachaphibulkij, K ; Kroemer, G; Brenner, C; Pervaiz, S 
42006Cleavage of misfolded nuclear receptor corepressor confers resistance to unfolded protein response-induced apoptosisNg, A.P.P.; Fong, J.H.; Nin, D.S.; Chen, C.-S. ; Pervaiz, S. ; Khan, M. ; Hirpara, J.L. ; Asou, N.
52003Decrease in intracellular superoxide sensitizes Bcl-2-overexpressing tumor cells to receptor and drug-induced apoptosis independent of the mitochondriaClement, M.-V. ; Hirpara, J.L. ; Pervaiz, S. 
617-Jul-2017Do STAT3 inhibitors have potential in the future for cancer therapy?Andrea Wong; Gautam Sethi ; Boon-Cher Goh ; Hirpara J.L. ; Pervaiz S. ; Eu J.Q. 
728-May-2013FLIP: A flop for execution signalsSubramaniam, K.; Hirpara, J.L. ; Tucker-Kellogg, L. ; Tucker-Kellogg, G. ; Pervaiz, S.
82004Hydrogen peroxide-mediated cytosolic acidification is a signal for mitochondrial translocation of bax during drug-induced apoptosis of tumor cellsAhmad, K.A.; Iskandar, K.B. ; Hirpara, J.L. ; Pervaiz, S. ; Clement, M.-V. 
91-Mar-2000Induction of mitochondrial permeability transition and cytochrome C release in the absence of caspase activation is insufficient for effective apoptosis in human leukemia cellsHirpara, J.L. ; Seyed, M.A. ; Loh, K.W.; Dong, H. ; Kini, R.M. ; Pervaiz, S. 
102000Induction of mitochondrial permeability transition and cytochrome C release in the absence of caspase activation is insufficient for effective apoptosis in human leukemia cellsPervaiz, S. ; Hirpara, J.L. ; Seyed, M.A.; Loh, K.W.; Dong, H. ; Kini, R.M. 
113-Nov-2021Interplay between Mitochondrial Metabolism and Cellular Redox State Dictates Cancer Cell SurvivalFoo, Brittney Joy-Anne; Eu, Jie Qing ; Hirpara, Jayshree L ; Pervaiz, Shazib 
122007LY303511 amplifies TRAIL-induced apoptosis in tumor cells by enhancing DR5 oligomerization, DISC assembly, and mitochondrial permeabilizationPoh, T.W.; Huang, S.; Hirpara, J.L. ; Pervaiz, S. 
1320-Aug-2016Manganese Superoxide Dismutase Expression Regulates the Switch Between an Epithelial and a Mesenchymal-Like Phenotype in Breast CarcinomaLoo, Ser Yue ; Hirpara, Jayshree L ; Pandey, Vijay ; Tan, Tuan Zea ; Yap, Celestial T ; Lobie, Peter E ; Thiery, Jean Paul ; Goh, Boon Cher ; Pervaiz, Shazib ; Clement, Marie-Veronique ; Kumar, Alan Prem 
141-Jul-2019Metabolic reprogramming of oncogene-addicted cancer cells to OXPHOS as a mechanism of drug resistanceHirpara, Jayshree ; Eu, Jie Qing ; Tan, Joanna Kia Min; Wong, Andrea L. ; Clement, Marie-Veronique ; Kong, Li Ren ; Ohi, Naoto; Tsunoda, Takeshi; Qu, Jianhua ; Goh, Boon Cher ; Pervaiz, Shazib 
152015Overexpression of Bcl-2 induces STAT-3 activation via an increase in mitochondrial superoxideKang, J ; Fei Chong, S.J ; Qi Ooi, V.Z; Vali, S; Kumar, A; Kapoor, S; Abbasi, T; Hirpara, J.L ; Loh, T ; Goh, B.C ; Pervaiz, S 
1628-Mar-2018Pan-HDAC inhibition by panobinostat mediates chemosensitization to carboplatin in non-small cell lung cancer via attenuation of EGFR signalingWang, Lingzhi ; Syn, Nicholas Li-Xun; Subhash, Vinod Vijay; Any, Yijia; Thuya, Win Lwin ; Cheow, Esther Sok Hwee ; Kong, Li Ren ; Yu, Fenggang ; Peethala, Praveen C. ; Wong, Andrea Li-Ann ; Laljibhai, Hirpara J. ; Chinnathambi, Arunachalam; Ong, Pei Shi ; Ho, Paul Chi-Lui ; Sethi, Gautam ; Yong, Wei Peng ; Goh, Boon Cher 
172020Peroxynitrite promotes serine-62 phosphorylation-dependent stabilization of the oncoprotein c-MycRaman, D. ; Chong, Stephen J. F. ; Iskandar, K. ; Hirpara, J.L. ; Pervaiz, S. 
182015Phase I and biomarker study of OPB-51602, a novel signal transducer and activator of transcription (STAT) 3 inhibitor, in patients with refractory solid malignanciesWong, Andrea; Soo, Ross A.; Tan, Daniel; Lee, Soo Chin ; Lim, Joline S J; Marban, P.C.; Kong, Li Ren ; Lee, Youngjoo; Wang, Lingzhi ; Thuya, Win Lwin ; Soong, R.; Yee, M.Q.; Chin, T.M.; Cordero, Maricel Tiemsim; Asuncion, Bernadette Reyna ; Pang, B.; Pervaiz, Shazib ; Hirpara, Jayshree L. ; Sinha, Arvind; Xu, W.W.; Yuasa, M.; Tsunoda, T.; Motoyama, M.; Yamauchi, T.; Goh, Boon Cher 
191999Purified photoproducts of merocyanine 540 trigger cytochrome C release and caspase 8-dependent apoptosis in human leukemia and melanoma cellsPervaiz, S. ; Seyed, M.A.; Hirpara, J.L. ; Clement, M.-V. ; Loh, K.W.
202010Simultaneous induction of non-canonical autophagy and apoptosis in cancer cells by ROS-dependent ERK and JNK activationWong, C.H.; Iskandar, K.B. ; Yadav, S.K.; Hirpara, J.L. ; Loh, T.; Pervaiz, S.