Full Name
Hirpara, J.L.
Hirpara, Jayshree L.
Main Affiliation


Results 1-15 of 15 (Search time: 0.006 seconds).

Issue DateTitleAuthor(s)
12006Cleavage of misfolded nuclear receptor corepressor confers resistance to unfolded protein response-induced apoptosisNg, A.P.P.; Fong, J.H.; Nin, D.S.; Chen, C.-S. ; Pervaiz, S. ; Khan, M. ; Hirpara, J.L. ; Asou, N.
22003Decrease in intracellular superoxide sensitizes Bcl-2-overexpressing tumor cells to receptor and drug-induced apoptosis independent of the mitochondriaClement, M.-V. ; Hirpara, J.L. ; Pervaiz, S. 
317-Jul-2017Do STAT3 inhibitors have potential in the future for cancer therapy?Andrea Wong; Gautam Sethi ; Boon-Cher Goh ; Hirpara J.L. ; Pervaiz S. ; Eu J.Q. 
428-May-2013FLIP: A flop for execution signalsSubramaniam, K.; Hirpara, J.L. ; Tucker-Kellogg, L. ; Tucker-Kellogg, G. ; Pervaiz, S.
52004Hydrogen peroxide-mediated cytosolic acidification is a signal for mitochondrial translocation of bax during drug-induced apoptosis of tumor cellsAhmad, K.A.; Iskandar, K.B. ; Hirpara, J.L. ; Pervaiz, S. ; Clement, M.-V. 
62000Induction of mitochondrial permeability transition and cytochrome C release in the absence of caspase activation is insufficient for effective apoptosis in human leukemia cellsPervaiz, S. ; Hirpara, J.L. ; Seyed, M.A.; Loh, K.W.; Dong, H. ; Kini, R.M. 
71-Mar-2000Induction of mitochondrial permeability transition and cytochrome C release in the absence of caspase activation is insufficient for effective apoptosis in human leukemia cellsHirpara, J.L. ; Seyed, M.A. ; Loh, K.W.; Dong, H. ; Kini, R.M. ; Pervaiz, S. 
82007LY303511 amplifies TRAIL-induced apoptosis in tumor cells by enhancing DR5 oligomerization, DISC assembly, and mitochondrial permeabilizationPoh, T.W.; Huang, S.; Hirpara, J.L. ; Pervaiz, S. 
91-Jul-2019Metabolic reprogramming of oncogene-addicted cancer cells to OXPHOS as a mechanism of drug resistanceHirpara, Jayshree ; Eu, Jie Qing ; Tan, Joanna Kia Min; Wong, Andrea L. ; Clement, Marie-Veronique ; Kong, Li Ren ; Ohi, Naoto; Tsunoda, Takeshi; Qu, Jianhua ; Goh, Boon Cher ; Pervaiz, Shazib 
102015Phase I and biomarker study of OPB-51602, a novel signal transducer and activator of transcription (STAT) 3 inhibitor, in patients with refractory solid malignanciesWong, Andrea; Soo, Ross A.; Tan, Daniel; Lee, Soo Chin ; Lim, Joline S J; Marban, P.C.; Kong, Li Ren ; Lee, Youngjoo; Wang, Lingzhi ; Thuya, Win Lwin ; Soong, R.; Yee, M.Q.; Chin, T.M.; Cordero, Maricel Tiemsim; Asuncion, Bernadette Reyna ; Pang, B.; Pervaiz, Shazib ; Hirpara, Jayshree L. ; Sinha, Arvind; Xu, W.W.; Yuasa, M.; Tsunoda, T.; Motoyama, M.; Yamauchi, T.; Goh, Boon Cher 
111999Purified photoproducts of merocyanine 540 trigger cytochrome C release and caspase 8-dependent apoptosis in human leukemia and melanoma cellsPervaiz, S. ; Seyed, M.A.; Hirpara, J.L. ; Clement, M.-V. ; Loh, K.W.
122010Simultaneous induction of non-canonical autophagy and apoptosis in cancer cells by ROS-dependent ERK and JNK activationWong, C.H.; Iskandar, K.B. ; Yadav, S.K.; Hirpara, J.L. ; Loh, T.; Pervaiz, S.
131999Superoxide anion inhibits drug-induced tumor cell deathPervaiz, S. ; Hirpara, J.L. ; Ramalingam, J.K. ; Clement, M.-V. 
142019Targeting STAT3 and oxidative phosphorylation in oncogene-addicted tumorsLee M.; Hirpara J.L. ; Eu J.-Q. ; Sethi G. ; Wang L. ; Goh B.-C. ; Wong A.L. 
159-Jun-2011The small GTPase Rac1 is a novel binding partner of Bcl-2 and stabilizes its antiapoptotic activityVelaithan, R. ; Kang, J.; Hirpara, J.L. ; Loh, T.; Goh, B.C.; Le Bras, M.; Brenner, C.; Clement, M.-V. ; Pervaiz, S.