Full Name
Koo Hao Mang, Edward
(not current staff)
Main Affiliation
 
 
Email
mdckhme@nus.edu.sg
 
Other emails
 

Publications

Results 1-16 of 16 (Search time: 0.014 seconds).

Issue DateTitleAuthor(s)
12016Alzheimer's disease risk polymorphisms regulate gene expression in the ZCWPW1 and the CELF1 lociKarch C.M.; Ezerskiy L.A.; Bertelsen S.; Goate A.M.; Albert M.S.; Albin R.L.; Apostolova L.G.; Arnold S.E.; Baldwin C.T.; Barber R.; Barmada M.M.; Barnes L.L.; Beach T.G.; Beecham G.W.; Beekly D.; Bennett D.A.; Bigio E.H.; Bird T.D.; Blacker D.; Boeve B.F.; Bowen J.D.; Boxer A.; Burke J.R.; Buxbaum J.D.; Cairns N.J.; Cantwell L.B.; Cao C.; Carlson C.S.; Carney R.M.; Carrasquillo M.M.; Carroll S.L.; Chui H.C.; Clark D.G.; Corneveaux J.; Crane P.K.; Cribbs D.H.; Crocco E.A.; Cruchaga C.; De Jager P.L.; DeCarli C.; DeKosky S.T.; Demirci F.Y.; Dick M.; Dickson D.W.; Duara R.; Ertekin-Taner N.; Evans D.; Faber K.M.; Fallon K.B.; Farlow M.R.; Ferris S.; Foroud T.M.; Frosch M.P.; Galasko D.R.; Ganguli M.; Gearing M.; Geschwind D.H.; Ghetti B.; Gilbert J.R.; Gilman S.; Glass J.D.; Graff-Radford N.R.; Green R.C.; Growdon J.H.; Hakonarson H.; Hamilton-Nelson K.L.; Hamilton R.L.; Hardy J.; Harrell L.E.; Head E.; Honig L.S.; Huentelman M.J.; Hulette C.M.; Hyman B.T.; Jarvik G.P.; Jicha G.A.; Jin L.-W.; Kamboh M.I.; Karydas A.; Kauwe J.S.K.; Kaye J.A.; Kim R.; Koo E.H. ; Kowall N.W.; Kramer J.H.; Kramer P.; Kukull W.A.; LaFerla F.M.; Lah J.J.; Larson E.B.; Leverenz J.B.; Levey A.I.; Li G.; Lin C.-F.; Lieberman A.P.; Lopez O.L.; Lunetta K.L.; Lyketsos C.G.; Mack W.J.; Marson D.C.; Martin E.R.; Martiniuk F.; Mash D.C.; Masliah E.; McCormick W.C.; McCurry S.M.; McDavid A.N.; McKee A.C.; Mesulam M.; Miller B.L.; Miller C.A.; Miller J.W.; Montine T.J.; Morris J.C.; Murrell J.R.; Myers A.J.; Naj A.C.; Olichney J.M.; Pankratz V.S.; Parisi J.E.; Peskind E.; Petersen R.C.; Pierce A.; Poon W.W.; Potter H.; Quinn J.F.; Raj A.; Rajbhandary R.A.; Raskind M.; Reiman E.M.; Reisberg B.; Reitz C.; Ringman J.M.; Roberson E.D.; Rogaeva E.; Rosen H.J.; Rosenberg R.N.; Sano M.; Saykin A.J.; Schneider J.A.; Schneider L.S.; Seeley W.W.; Smith A.G.; Sonnen J.A.; Spina S.; Stern R.A.; Tanzi R.E.; Trojanowski J.Q.; Troncoso J.C.; Tsuang D.W.; Valladares O.; Van Deerlin V.M.; Van Eldik L.J.; Vardarajan B.N.; Vinters H.V.; Vonsattel J.P.; Weintraub S.; Welsh-Bohmer K.A.; Williamson J.; Woltjer R.L.; Wright C.B.; Younkin S.G.; Yu C.-E.; Yu L.
222018APP upregulation contributes to retinal ganglion cell degeneration via JNK3Liu C. ; Zhang C.-W.; Zhou Y. ; Wong W.Q.; Lee L.C. ; Ong W.Y. ; Yoon S.O.; Hong W.; Fu X.-Y. ; Soong T.W. ; Koo E.H. ; Stanton L.W.; Lim K.-L. ; Xiao Z.-C.; Dawe G.S. 
32011Biology and pathophysiology of the amyloid precursor proteinZheng H.; Koo E.H. 
42020Caspase Activation and Caspase-Mediated Cleavage of APP Is Associated with Amyloid ?-Protein-Induced Synapse Loss in Alzheimer's DiseasePark, G.; Nhan, H.S.; Tyan, S.-H.; Kawakatsu, Y.; Zhang, C.; Navarro, M.; Koo, E.H. 
52015Cholestenoic acid, an endogenous cholesterol metabolite, is a potent ?-secretase modulatorJung J.I.; Price A.R.; Ladd T.B.; Ran Y.; Park H.-J.; Ceballos-Diaz C.; Smithson L.A.; Hochhaus G.; Tang Y.; Akula R.; Ba S.; Koo E.H. ; Shapiro G.; Felsenstein K.M.; Golde T.E.
62007Chronic administration of R-flurbiprofen attenuates learning impairments in transgenic amyloid precursor protein miceKukar T.; Prescott S.; Eriksen J.L.; Holloway V.; Murphy M.P.; Koo E.H. ; Golde T.E.; Nicolle M.M.
7May-2023Chronic cerebral hypoperfusion alters the CypA-EMMPRIN-gelatinase pathway: Implications for vascular dementiaChai, Yuek Ling ; Rajeev, Vismitha ; Poh, Luting ; Selvaraji, Sharmelee ; Hilal, Saima ; Chen, Christopher P ; Jo, Dong-Gyu; Koo, Edward H ; Arumugam, Thiruma ; Lai, Mitchell KP 
81-Jan-2019Evidence that NLRC4 inflammasome mediates apoptotic and pyroptotic microglial death following ischemic strokePoh, Luting ; Kang, Sung-Wook ; Baik, Sang-Ha ; Ng, Gavin Yong Quan; She, David T; Balaganapathy, Priyanka; Dheen, S Thameem ; Magnus, Tim; Gelderblom, Mathias; Sobey, Christopher G; Koo, Edward H ; Fann, David Y ; Arumugam, Thiruma V 
92014Independent Relationship between Amyloid Precursor Protein (APP) Dimerization and γ-Secretase ProcessivityJung J.I.; Premraj S.; Cruz P.E.; Ladd T.B.; Kwak Y.; Koo E.H. ; Felsenstein K.M.; Golde T.E.; Ran Y.
102015Inter-dependent mechanisms behind cognitive dysfunction, vascular biology and Alzheimer’s dementia in down syndrome: Multi-faceted roles of APPNizetic, D; Chen, C.L ; Hong, W ; Koo, E.H 
112015Modulation of Aβ42 in vivo by γ-secretase modulator in primates and humansLing, I.-F; Golde, T.E; Galasko, D.R; Koo, E.H 
121-Jan-2021SINgapore GERiatric intervention study to reduce physical frailty and cognitive decline (SINGER)–pilot: A feasibility studyChew, KA ; Xu, X; Siongco, P; Villaraza, S; Phua, AKS ; Wong, ZX ; Chung, CY; Tang, N ; Chew, E ; Henry, CJ ; Koo, E ; Chen, C 
132014Specific disruption of hippocampal mossy fiber synapses in a mouse model of familial Alzheimer's diseaseWilke S.A.; Raam T.; Antonios J.K.; Bushong E.A.; Koo E.H. ; Ellisman M.H.; Ghosh A.
144-May-2019The ALS-FTD-linked gene product, C9orf72, regulates neuronal morphogenesis via autophagyHO, WAN YUN ; TAI, YEE KIT ; CHANG, JER-CHERNG ; LIANG, JASON; TYAN, SHEUE-HOUY ; CHEN, SONG; GUAN, JUN-LIN; ZHOU, HUILIN; SHEN, HAN-MING ; KOO, EDWARD ; LING, SHUO-CHIEN 
152006The amyloid precursor protein: Beyond amyloidZheng H.; Koo E.H. 
162015γ-Secretase Modulators and APH1 Isoforms Modulate γ-Secretase Cleavage but Not Position of ε-Cleavage of the Amyloid Precursor Protein (APP)Lessard C.B.; Cottrell B.A.; Maruyama H.; Suresh S.; Golde T.E.; Koo E.H.