Full Name
Shuo-Chien Ling
Variants
Ling S.-C.
 
Main Affiliation
 
 
Email
phsling@nus.edu.sg
 
 

Publications

Results 1-16 of 16 (Search time: 0.037 seconds).

Issue DateTitleAuthor(s)
128-Jun-2022A degradative to secretory autophagy switch mediates mitochondria clearance in the absence of the mATG8-conjugation machineryTan, Hayden Weng Siong ; Lu, Guang; Dong, Han ; Cho, Yik-Lam ; Natalia, Auginia ; Wang, Liming ; Chan, Charlene ; Kappei, Dennis ; Taneja, Reshma ; Ling, Shuo-Chien ; Shao, Huilin ; Tsai, Shih-Yin ; Ding, Wen-Xing; Shen, Han-Ming 
22015ALS-causative mutations in FUS/TLS confer gain and loss of function by altered association with SMN and U1-snRNPSun S.; Ling S.-C. ; Qiu J.; Albuquerque C.P.; Zhou Y.; Tokunaga S.; Li H.; Qiu H.; Bui A.; Yeo G.W.; Huang E.J.; Eggan K.; Zhou H.; Fu X.-D.; Lagier-Tourenne C.; Cleveland D.W.
31-Nov-2019C9orf72 intermediate repeats are associated with corticobasal degeneration, increased C9orf72 expression and disruption of autophagyCali, Christopher P; Patino, Maribel; Tai, Yee Kit ; Ho, Wan Yun ; McLean, Catriona A; Morris, Christopher M; Seeley, William W; Miller, Bruce L; Gaig, Carles; Vonsattel, Jean Paul G; White, Charles L; Roeber, Sigrun; Kretzschmar, Hans; Troncoso, Juan C; Troakes, Claire; Gearing, Marla; Ghetti, Bernardino; Van Deerlin, Vivianna M; Lee, Virginia M-Y; Trojanowski, John Q; Mok, Kin Y; Ling, Helen; Dickson, Dennis W; Schellenberg, Gerard D; Ling, Shuo-Chien ; Lee, Edward B
41-Dec-2022Deciphering lipid dysregulation in ALS: from mechanisms to translational medicineAgrawal, I ; Lim, YS ; Ng, SY ; Ling, SC 
52020Deregulated expression of a longevity gene, Klotho, in the C9orf72 deletion mice with impaired synaptic plasticity and adult hippocampal neurogenesisHo, W.Y. ; Navakkode, Sheeja ; Liu, F. ; Soong, Tuck Wah ; Ling, S.-C. 
66-Jan-2021Dysfunction in nonsense-mediated decay, protein homeostasis, mitochondrial function, and brain connectivity in ALS-FUS mice with cognitive deficitsHo, Wan Yun ; Agrawal, Ira ; Tyan, Sheue-Houy ; Sanford, Emma ; Chang, Wei-Tang; Lim, Kenneth ; Ong, Jolynn; Tan, Bernice Siu Yan; Moe, Aung Aung Kywe; Yu, Regina; Wong, Peiyan ; Tucker-Kellogg, Greg ; Koo, Edward; Chuang, Kai-Hsiang; Ling, Shuo-Chien 
723-Jun-2019Elevated FUS levels by overriding its autoregulation produce gain-of-toxicity properties that disrupt protein and RNA homeostasisWan Yun Ho ; Shuo-Chien Ling 
82016FUS-linked essential tremor associated with motor dysfunction in DrosophilaTio M.; Wen R.; Lim Y.L.; Wang H.; Ling S.-C. ; Zhao Y.; Tan E.-K. 
92013Fused in sarcoma (FUS) protein lacking nuclear localization signal (NLS) and major RNA binding motifs triggers proteinopathy and severe motor phenotype in transgenic miceShelkovnikova, T.A; Peters, O.M; Deykin, A.V; Connor-Robson, N; Robinson, H; Ustyugov, A.A; Bachurin, S.O; Ermolkevich, T.G; Goldman, I.L; Sadchikova, E.R; Kovrazhkina, E.A; Skvortsova, V.I; Ling, S.-C ; Da Cruz, S; Parone, P.A; Buchman, V.L; Ninkina, N.N
108-Feb-2021Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)Ling Shuo-Chien ; HO WAN YUN 
112017Mutant TDP-43 within motor neurons drives disease onset but not progression in amyotrophic lateral sclerosisDitsworth, D; Maldonado, M; McAlonis-Downes, M; Sun, S; Seelman, A; Drenner, K; Arnold, E; Ling, S.-C ; Pizzo, D; Ravits, J; Cleveland, D.W; Da Cruz, S
122019Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axisLing, S.-C. ; Dastidar, S.G.; Tokunaga, S.; Ho, W.Y. ; Lim, K. ; Ilieva, H.; Parone, P.A.; Tyan, S.-H. ; Tse, T.M. ; Chang, J.-C.; Platoshyn, O.; Bui, N.B.; Bui, A.; Vetto, A.; Sun, S.; McAlonis-Downes, M.; Han, J.S.; Swing, D.; Kapeli, K. ; Yeo, G.W. ; Tessarollo, L.; Marsala, M.; Shaw, C.E.; Tucker-Kellogg, G. ; La Spada, A.R.; Lagier-Tourenne, C.; Da Cruz, S.; Cleveland, D.W.
132018Synaptic paths to neurodegeneration: The emerging role of TDP-43 and FUS in synaptic functionsLing, S.-C 
1410-Mar-2021TDP-43 maximizes nerve conduction velocity by repressing a cryptic exon for paranodal junction assembly in Schwann cellsChang, Kae-Jiun; Agrawal, Ira ; Vainshtein, Anna; Ho, Wan Yun ; Xin, Wendy; Tucker-Kellogg, Greg ; Susuki, Keiichiro; Peles, Elior; Ling, Shuo-Chien ; Chan, Jonah R.
154-May-2019The ALS-FTD-linked gene product, C9orf72, regulates neuronal morphogenesis via autophagyHO, WAN YUN ; TAI, YEE KIT ; CHANG, JER-CHERNG ; LIANG, JASON; TYAN, SHEUE-HOUY ; CHEN, SONG; GUAN, JUN-LIN; ZHOU, HUILIN; SHEN, HAN-MING ; KOO, EDWARD ; LING, SHUO-CHIEN 
162015Wild type human TDP-43 potentiates ALS-linked mutant TDP-43 driven progressive motor and cortical neuron degeneration with pathological features of ALSMitchell, J.C; Constable, R; So, E; Vance, C; Scotter, E; Glover, L; Hortobagyi, T; Arnold, E.S; Ling, S.-C ; McAlonis, M; Da Cruz, S; Polymenidou, M; Tessarolo, L; Cleveland, D.W; Shaw, C.E