Full Name
Ling S.-C.
Variants
Ling S.-C.
 
Main Affiliation
 
 
Email
gmslsc@nus.edu.sg
 
Other emails
 

Publications

Results 1-10 of 10 (Search time: 0.035 seconds).

Issue DateTitleAuthor(s)
12015ALS-causative mutations in FUS/TLS confer gain and loss of function by altered association with SMN and U1-snRNPSun S.; Ling S.-C. ; Qiu J.; Albuquerque C.P.; Zhou Y.; Tokunaga S.; Li H.; Qiu H.; Bui A.; Yeo G.W.; Huang E.J.; Eggan K.; Zhou H.; Fu X.-D.; Lagier-Tourenne C.; Cleveland D.W.
22020Deregulated expression of a longevity gene, Klotho, in the C9orf72 deletion mice with impaired synaptic plasticity and adult hippocampal neurogenesisHo, W.Y. ; Navakkode, Sheeja ; Liu, F. ; Soong, Tuck Wah ; Ling, S.-C. 
323-Jun-2019Elevated FUS levels by overriding its autoregulation produce gain-of-toxicity properties that disrupt protein and RNA homeostasisWan Yun Ho ; Shuo-Chien Ling 
42016FUS-linked essential tremor associated with motor dysfunction in DrosophilaTio M.; Wen R.; Lim Y.L.; Wang H.; Ling S.-C. ; Zhao Y.; Tan E.-K. 
52013Fused in sarcoma (FUS) protein lacking nuclear localization signal (NLS) and major RNA binding motifs triggers proteinopathy and severe motor phenotype in transgenic miceShelkovnikova, T.A; Peters, O.M; Deykin, A.V; Connor-Robson, N; Robinson, H; Ustyugov, A.A; Bachurin, S.O; Ermolkevich, T.G; Goldman, I.L; Sadchikova, E.R; Kovrazhkina, E.A; Skvortsova, V.I; Ling, S.-C ; Da Cruz, S; Parone, P.A; Buchman, V.L; Ninkina, N.N
68-Feb-2021Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)Ling Shuo-Chien ; HO WAN YUN 
72017Mutant TDP-43 within motor neurons drives disease onset but not progression in amyotrophic lateral sclerosisDitsworth, D; Maldonado, M; McAlonis-Downes, M; Sun, S; Seelman, A; Drenner, K; Arnold, E; Ling, S.-C ; Pizzo, D; Ravits, J; Cleveland, D.W; Da Cruz, S
82018Synaptic paths to neurodegeneration: The emerging role of TDP-43 and FUS in synaptic functionsLing, S.-C 
94-May-2019The ALS-FTD-linked gene product, C9orf72, regulates neuronal morphogenesis via autophagyHO, WAN YUN ; TAI, YEE KIT ; CHANG, JER-CHERNG ; LIANG, JASON; TYAN, SHEUE-HOUY ; CHEN, SONG; GUAN, JUN-LIN; ZHOU, HUILIN; SHEN, HAN-MING ; KOO, EDWARD ; LING, SHUO-CHIEN 
102015Wild type human TDP-43 potentiates ALS-linked mutant TDP-43 driven progressive motor and cortical neuron degeneration with pathological features of ALSMitchell, J.C; Constable, R; So, E; Vance, C; Scotter, E; Glover, L; Hortobagyi, T; Arnold, E.S; Ling, S.-C ; McAlonis, M; Da Cruz, S; Polymenidou, M; Tessarolo, L; Cleveland, D.W; Shaw, C.E