Please use this identifier to cite or link to this item: https://doi.org/10.1002/trc2.12141
Title: SINgapore GERiatric intervention study to reduce physical frailty and cognitive decline (SINGER)–pilot: A feasibility study
Authors: Chew, KA 
Xu, X
Siongco, P
Villaraza, S
Phua, AKS 
Wong, ZX 
Chung, CY
Tang, N 
Chew, E 
Henry, CJ 
Koo, E 
Chen, C 
Keywords: cognitive impairment
dementia
feasibility
intervention
lifestyle
randomized controlled trial
Issue Date: 1-Jan-2021
Publisher: Wiley
Citation: Chew, KA, Xu, X, Siongco, P, Villaraza, S, Phua, AKS, Wong, ZX, Chung, CY, Tang, N, Chew, E, Henry, CJ, Koo, E, Chen, C (2021-01-01). SINgapore GERiatric intervention study to reduce physical frailty and cognitive decline (SINGER)–pilot: A feasibility study. Alzheimer's and Dementia: Translational Research and Clinical Interventions 7 (1) : e12141-. ScholarBank@NUS Repository. https://doi.org/10.1002/trc2.12141
Abstract: Introduction: The SINGER pilot randomized controlled trial aims to examine the feasibility and acceptability of the Finnish Geriatric Intervention Study (FINGER) multi-domain lifestyle interventions compared to Singaporean adaptations. Methods: Seventy elderly participants were recruited and randomized into FINGER (n = 36) or SINGER (n = 34) interventions; involving physical exercise, cognitive training, diet, and vascular risk factors management, for 6 months. Results: Both intervention groups were equally feasible and acceptable with participants completing at least 80% of the interventions. Body strength improved in both groups (Pupper body =.04, Plower body =.06, Pcore =.05). More participants in the SINGER group attained good blood pressure control at month-6 compared to FINGER (41% vs 19%; P =.06). Discussion: This study is the first to compare the feasibility of multi-domain interventions adapted to local culture with the FINGER interventions. The findings will be utilized for a larger study to provide evidence for the efficacy of multi-domain lifestyle interventions in preventing cognitive decline.
Source Title: Alzheimer's and Dementia: Translational Research and Clinical Interventions
URI: https://scholarbank.nus.edu.sg/handle/10635/218778
ISSN: 2352-8737
DOI: 10.1002/trc2.12141
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