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Tuan Zea Tan

rp01843

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Full Name
Tuan Zea Tan
Variants
Tan, T.Z.
Tan, Tuan Zea
 
Main Affiliation
 
Faculty
 
Email
csittz@nus.edu.sg
 

Publications

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Department:  DEAN'S OFFICE (MEDICINE)
Type:  Article

Results 1-20 of 24 (Search time: 0.017 seconds).

Issue DateTitleAuthor(s)
12018A loss-of-function genetic screening reveals synergistic targeting of AKT/mTOR and WTN/β-catenin pathways for treatment of AML with high PRL-3 phosphataseZhou, J ; Toh, S.H.-M; Chan, Z.-L; Quah, J.Y; Chooi, J.-Y ; Tan, T.Z ; Chong, P.S.Y ; Zeng, Q ; Chng, W.-J 
21-Sep-2020ASLAN003, a potent dihydroorotate dehydrogenase inhibitor for differentiation of acute myeloid leukemia.Zhou, Jianbiao ; Yiying Quah, Jessie ; Ng, Yvonne ; Chooi, Jing-Yuan ; Hui-Min Toh, Sabrina ; Lin, Baohong; Zea Tan, Tuan ; Hosoi, Hiroki ; Osato, Motomi ; Seet, Qihui; Ooi, Lisa AG; Lindmark, Bertil; McHale, Mark; Chng, Wee-Joo 
3Jul-2017Belinostat exerts antitumor cytotoxicity through the ubiquitin-proteasome pathway in lung squamous cell carcinomaKong, L.R ; Tan, T.Z ; Ong, W.R; Bi, C; Huynh, H ; Lee, S.C ; Chng, W.J ; Eichhorn, P.J.A ; Goh, B.C 
411-Jul-2018BET Bromodomain inhibition promotes De-repression of TXNIP and activation of ASK1-MAPK pathway in acute myeloid leukemiaZhou Y.; Zhou J. ; Lu X.; Tan T.-Z. ; Chng W.-J. 
5Dec-2019c-Met activation leads to the establishment of a TGFβ-receptor regulatory network in bladder cancer progressionSim, Wen Jing ; Iyengar, Prasanna Vasudevan ; Lama, Dilraj; Lui, Sarah Kit Leng ; Ng, Hsien Chun ; Haviv-Shapira, Lior; Domany, Eytan; Kappei, Dennis ; Tan, Tuan Zea ; Saie, Azad; Jaynes, Patrick William ; Verma, Chandra Shekhar ; Kumar, Alan Prem ; Rouanne, Mathieu; Ha, Hong Koo; Radulescu, Camelia; ten Dijke, Peter; Eichhorn, Pieter Johan Adam ; Thiery, Jean Paul 
618-Jan-2019Cytoskeletal Proteins in Cancer and Intracellular Stress: A Therapeutic PerspectiveOng, Mei Shan; Deng, Shuo ; Halim, Clarissa Esmeralda ; Cai, Wanpei ; Tan, Tuan Zea ; Huang, Ruby Yun-Ju ; Sethi, Gautam ; Hooi, Shing Chuan ; Kumar, Alan Prem ; Yap, Celestial T 
727-Sep-2021Epigenetic derepression converts PPAR gamma into a druggable target in triple-negative and endocrine-resistant breast cancersLoo, Ser Yue; Syn, Nicholas L; Koh, Angele Pei-Fern ; Teng, Janet Cheng-Fei ; Deivasigamani, Amudha; Tan, Tuan Zea ; Thike, Aye Aye ; Vali, Shireen ; Kapoor, Shweta; Wang, Xiaoyuan ; Wang, Jiong Wei ; Tan, Puay Hoon ; Yip, George W ; Sethi, Gautam ; Huang, Ruby Yun-Ju ; Hui, Kam Man ; Wang, Lingzhi ; Goh, Boon Cher ; Kumar, Alan Prem 
829-Jun-2016Functional characterization of selective exosite-binding inhibitors of Matrix metalloproteinase-13 (MMP-13) – experimental validation in human breast and colon cancerKodappully Siveen ; Tuan Zea Tan ; Jean-Paul Thierry ; Alan Prem Kumar ; Gautam Sethi ; Kunchithapadam Swaminathan 
915-Sep-2019IL6 Promotes a STAT3-PRL3 Feedforward Loop via SHP2 Repression in Multiple MyelomaChong, Phyllis SY ; Zhou, Jianbiao ; Lim, Julia SL ; Hee, Yan Ting; Chooi, Jing-Yuan ; Chung, Tae-Hoon ; Tan, Zea Tuan ; Zeng, Qi ; Waller, Daniel D; Sebag, Michael; Chng, Wee-Joo 
102017Inhibition of LIN28B impairs leukemia cell growth and metabolism in acute myeloid leukemiaZhou, J ; Bi, C; Ching, Y.Q ; Chooi, J.-Y ; Lu, X; Quah, J.Y ; Toh, S.H.-M ; Chan, Z.-L; Tan, T.Z ; Chong, P.S ; Chng, W.-J 
111-Mar-2017LIN28B Activation by PRL-3 Promotes Leukemogenesis and a Stem Cell-like Transcriptional Program in AMLZhou, Jianbiao ; Chan, Zit-Liang; Bi, Chonglei; Lu, Xiao; Chong, Phyllis SY ; Chooi, Jing-Yuan ; Cheong, Lip-Lee; Liu, Shaw-Cheng; Ching, Ying Qing ; Zhou, Yafeng; Osato, Motomi; Tan, Tuan Zea ; Ng, Chin Hin ; Ng, Siok-Bian ; Wang, Shi ; Zeng, Qi ; Chng, Wee-Joo 
1220-Aug-2016Manganese Superoxide Dismutase Expression Regulates the Switch Between an Epithelial and a Mesenchymal-Like Phenotype in Breast CarcinomaLoo, Ser Yue ; Hirpara, Jayshree L ; Pandey, Vijay ; Tan, Tuan Zea ; Yap, Celestial T ; Lobie, Peter E ; Thiery, Jean Paul ; Goh, Boon Cher ; Pervaiz, Shazib ; Clement, Marie-Veronique ; Kumar, Alan Prem 
131-Jan-2021MicroRNA-196a promotes renal cancer cell migration and invasion by targeting BRAM1 to regulate SMAD and MAPK signaling pathwaysCui, Jianzhou ; Yuan, Yi; Shanmugam, Muthu K ; Anbalagan, Durkeshwari; Tan, Tuan Zea ; Sethi, Gautam ; Kumar, Alan Prem ; Lim, Lina HK 
1426-Apr-2018NF-kappa B promotes the stem-like properties of leukemia cells by activation of LIN28BZhou, Jianbiao ; Chooi, Jing-Yuan ; Ching, Ying Qing ; Quah, Jessie Yiying ; Toh, Sabrina Hui-Min ; Ng, Yvonne ; Tan, Tuan Zea ; Chng, Wee-Joo 
1528-Feb-2019Non-canonical activation of beta-catenin by PRL-3 phosphatase in acute myeloid leukemiaChong, Phyllis SY ; Zhou, Jianbiao ; Chooi, Jing-Yuan ; Chan, Zit-Liang; Toh, Sabrina Hui Min ; Tan, Tuan Zea ; Wee, Sheena; Gunaratne, Jayantha ; Zeng, Qi ; Chng, Wee-Joo 
162019Pharmacological inhibition of TFF3 enhances sensitivity of CMS4 colorectal carcinoma to 5-fluorouracil through inhibition of p44/42 MAPKChen, R.-M. ; Chiou, Y.-S.; Chong, Q.-Y. ; Poh, H.-M.; Tan, T.-Z. ; Zhang, M.-Y.; Ma, L.; Zhu, T.; Pandey, V.; Salundi, B.; Prem Kumar, A. ; Lobie, P.E. 
17Nov-2017PPARγ Ligand-induced Annexin A1 Expression Determines Chemotherapy Response via Deubiquitination of Death Domain Kinase RIP in Triple-negative Breast Cancers.Chen, Luxi ; Yuan, Yi; Kar, Shreya; Kanchi, Madhu M ; Arora, Suruchi; Kim, Ji E; Koh, Pei F ; Yousef, Einas; Samy, Ramar P ; Shanmugam, Muthu K ; Tuan Z ; Shin, Sung W; Arfuso, Frank; Shen, Han M ; Yang, Henry; Goh, Boon C ; Park, Joo I; Gaboury, Louis; Lobie, Peter E ; Sethi, Gautam ; Lim, Lina HK ; Kumar, Alan P 
182018RUNX1 and RUNX3 protect against YAP-mediated EMT, stemness and shorter survival outcomes in breast cancerKulkarni, M ; Tan, T.Z ; Sulaiman, N.B.s; Lamar, J.M; Bansal, P; Cui, J ; Qiao, Y ; Ito, Y 
1915-Dec-2023SHP2 inhibitors maintain TGFβ signalling through SMURF2 inhibitionLai, Xianning ; Lui, Sarah Kit Leng ; Lam, Hiu Yan ; Adachi, Yuta; Sim, Wen Jing ; Vasilevski, Natali; Armstrong, Nicola J; Bridgeman, Stephanie Claire; Main, Nathan Michael; Tan, Tuan Zea ; Tirnitz-Parker, Janina EE; Thiery, Jean Paul ; Ebi, Hiromichi; Kumar, Alan Prem ; Eichhorn, Pieter Johan Adam 
201-May-2021SMARCA2 Is a Novel Interactor of NSD2 and Regulates Prometastatic PTP4A3 through Chromatin Remodeling in t(4;14) Multiple MyelomaChong, Phyllis SY ; Chooi, Jing Yuan; Lim, Julia SL ; Toh, Sabrina Hui Min ; Tan, Tuan Zea ; Chng, Wee-Joo