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DEAN-MED-SYNTHETIC BIOLOGY TRANSLATIONAL RESEARCH PROGRAMME

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	Issue Date	Title	Author(s)
1	19-Mar-2021	Understanding and exploiting the fatty acid desaturation system in Rhodotorula toruloides	Liu, Yanbin; Koh, Chong Mei John ; Yap, Sihui Amy ; Cai, Lin; Ji, Lianghui
2	12-Feb-2021	Ubiquitin ligase smurf2 interacts with filovirus vp40 and promotes egress of vp40 vlps	Shepley-McTaggart, Ariel; Schwoerer, Michael Patrick; Sagum, Cari A.; Bedford, Mark T.; Jaladanki, Chaitanya K.; Fan, Hao ; Cassel, Joel; Harty, Ronald N.
3	2015	The Structural Basis for Activation and Inhibition of ZAP-70 Kinase Domain	Huber R.G.; Fan H. ; Bond P.J.
4	16-Nov-2021	Systems Biology to Understand and Regulate Human Retroviral Proinflammatory Response	Helmy, Mohamed; Selvarajoo, Kumar
5	2020	Systems biology approaches integrated with artificial intelligence for optimized metabolic engineering	Helmy, M.; Smith, D.; Selvarajoo, K.
6	2016	Synthetic genetic polymers: Advances and applications	Ma, Q ; Lee, D; Tan, Y.Q ; Wong, G ; Gao, Z
7	5-Apr-2022	Structure-Guided Engineering of Prenyltransferase NphB for High-Yield and Regioselective Cannabinoid Production	Lim, Kevin Jie Han ; Hartono, Yossa Dwi ; Xue, Bo ; Go, Maybelle Kho ; Fan, Hao ; Yew, Wen Shan
8	28-Jun-2021	Structure-based virtual screening of CYP1A1 inhibitors: towards rapid tier-one assessment of potential developmental toxicants	Goh, Janice Jia Ni; Behn, Julian; Chong, Cheng-Shoong; Zhong, Guorui; Maurer-Stroh, Sebastian ; Fan, Hao ; Loo, Lit-Hsin
9	2020	STAT3 Regulates Mouse Neural Progenitor Proliferation and Differentiation by Promoting Mitochondrial Metabolism	Su, Y.; Zhang, W.; Patro, C.P.K. ; Zhao, J.; Mu, T.; Ma, Z.; Xu, J.; Ban, K. ; Yi, C.; Zhou, Y.
10	2020	ScatLay: utilizing transcriptome-wide noise for identifying and visualizing differentially expressed genes	Bui, T.T.; Lee, D.; Selvarajoo, K.
11	7-Feb-2022	Reconstituting the complete biosynthesis of D-lysergic acid in yeast	Wong, Garrett ; Lim, Li Rong ; Tan, Yong Quan ; Go, Maybelle Kho; Bell, David J; Freemont, Paul S; Yew, Wen Shan
12	1-Jan-2022	Recent Advances in Structure, Function, and Pharmacology of Class A Lipid GPCRs: Opportunities and Challenges for Drug Discovery	Krishna Deepak, RNV; Verma, Ravi Kumar; Hartono, Yossa Dwi ; Yew, Wen Shan ; Fan, Hao
13	1-Sep-2019	Phage-boosted chemotherapy	NIKHIL AGGARWAL ; Hwang In Young ; Chang,Matthew Wook
14	2019	Organic cation transporter 3 (Oct3) is a distinct catecholamines clearance route in adipocytes mediating the beiging of white adipose tissue	Song, W.; Luo, Q.; Zhang, Y.; Zhou, L.; Liu, Y.; Ma, Z.; Guo, J.; Huang, Y.; Cheng, L.; Meng, Z.; Li, Z.; Zhang, B.; Li, S.; Yee, S.W.; Fan, H. ; Li, P.; Giacomini, K.M.; Chen, L.
15	13-Sep-2018	Oncogenic activation of the STAT3 pathway drives PD-L1 expression in natural killer/T-cell lymphoma	Song, Tammy Linlin; Nairismagi, Maarja-Liisa; Laurensia, Yurike; Lim, Jing-Quan ; Tan, Jing; Li, Zhi-Mei; Pang, Wan-Lu; Kizhakeyil, Atish; Wijaya, Giovani-Claresta; Huang, Da-Chuan; Nagarajan, Sanjanaa; Chia, Burton Kuan-Hui; Cheah, Daryl; Liu, Yan-Hui; Zhang, Fen; Rao, Hui-Lan; Tang, Tiffany; Wong, Esther Kam-Yin; Bei, Jin-Xin; Iqbal, Jabed; Grigoropoulos, Nicholas-Francis; Ng, Siok-Bian ; Chng, Wee-Joo ; Teh, Bin-Tean ; Tan, Soo-Yong; Verma, Navin Kumar; Fan, Hao ; Lim, Soon-Thye; Ong, Choon-Kiat
16	2020	Modular mimicry and engagement of the Hippo pathway by Marburg virus VP40: Implications for filovirus biology and budding	Han, Z.; Dash, S.; Sagum, C.A.; Ruthel, G.; Jaladanki, C.K.; Berry, C.T.; Schwoerer, M.P.; Harty, N.M.; Freedman, B.D.; Bedford, M.T.; Fan, H. ; Sidhu, S.S.; Sudol, M. ; Shtanko, O.; Harty, R.N.
17	16-Mar-2023	Increasing lysergic acid levels for ergot alkaloid biosynthesis: Directing catalysis via the F-G loop of Clavine oxidases	Lim, Li Rong ; Wong, Garrett ; Go, Maybelle KK; Yew, Wen Shan
18	2018	Identification of novel genes in the carotenogenic and oleaginous yeast Rhodotorula toruloides through genome-wide insertional mutagenesis	Liu, Y.; Koh, C.M.J. ; Yap, S.A. ; Du, M.; Hlaing, M.M. ; Ji, L.
19	1-Dec-2018	Homozygous mutation in MFSD2A, encoding a lysolipid transporter for docosahexanoic acid, is associated with microcephaly and hypomyelination	Harel, Tamar; Quek, Debra QY; Wong, Bernice H; Cazenave-Gassiot, Amaury; Wenk, Markus R ; Fan, Hao ; Berger, Itai; Shmueli, Dorit; Shaag, Avraham; Silver, David L; Elpeleg, Orly; Edvardson, Shimon
20	Mar-2021	Future trends in synthetic biology in Asia.	Mao, Ning ; Aggarwal, Nikhil ; Poh, Chueh Loo ; Cho, Byung Kwan; Kondo, Akihiko; Liu, Chenli; Yew, Wen Shan ; Chang, Matthew Wook