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Saji Kumar Sreedharan

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Full Name
Saji Kumar Sreedharan
Variants
Sreedharan, Sajikumar
Sajikumar, Sreedharan
 
Main Affiliation
 
Faculty
 
Email
phssks@nus.edu.sg
 

Publications

Results 1-20 of 21 (Search time: 0.015 seconds).

Issue DateTitleAuthor(s)
11-Feb-2021Age-related changes in hippocampal-dependent synaptic plasticity and memory mediated by p75 neurotrophin receptorWONG LIK WEI ; CARLOS F. IBANEZ ; SAJI KUMAR SREEDHARAN ; KISISWA, LILIAN ; SIM WEILING EUNICE 
18218-May-2016ApoE4 expression accelerates hippocampus-dependent cognitive deficits by enhancing A beta impairment of insulin signaling in an Alzheimer's disease mouse modelChan, Elizabeth S ; Shetty, Mahesh Shivarama ; Sajikumar, Sreedharan ; Chen, Christopher ; Soong, Tuck Wah ; Wong, Boon-Seng 
232017Chelation of hippocampal zinc enhances long-term potentiation and synaptic tagging/capture in CA1 pyramidal neurons of aged rats: implications to aging and memoryShetty, M.S ; Sharma, M ; Sajikumar, S 
42019Deletion of CD137 ligand exacerbates renal and cutaneous but alleviates cerebral manifestations in LupusMak, A. ; Dharmadhikari, B. ; Kow, N.Y. ; Thamboo, T.P. ; Tang, Q.; Wong, L.W. ; Sajikumar, S. ; Wong, H.Y. ; Schwarz, H. 
55-Jan-2023Distinct contributions of ventral CA1/amygdala co-activation to the induction and maintenance of synaptic plasticityChong, Yee Song ; Wong, Lik-Wei ; Gaunt, Jessica; Lee, Yan Jun ; Goh, Cai Shan; Morris, Richard GM; Ch'ng, Toh Hean; Sajikumar, Sreedharan 
62017Epigenetic regulation by G9a/GLP complex ameliorates amyloid-beta 1-42 induced deficits in long-term plasticity and synaptic tagging/capture in hippocampal pyramidal neuronsSharma, M ; Dierkes, T; Sajikumar, S 
726-Oct-2018Epigenetic regulation of microglial phosphatidylinositol 3-kinase (PI3K) by miR-21-5p and HDAC3 may be involved in memory and Alzheimer’s diseaseSaw, Genevieve; Krishna, Kumar ; Sreedharan, Sajikumar ; Dheen, Shaikali Thameem 
810-Dec-2017Epigenetic regulation of microglial phosphatidylinositol 3-kinase (PI3K)/protein kinase (Akt) pathway involved in synaptic plasticity (Invited Speaker)Dheen, ST ; Saw, Genevieve; Gupta, Neelima ; Mallilankaraman, Karthik ; Sreedharan, Sajikumar 
98-Nov-2019Epigenetic regulation of microglial phosphatidylinositol 3-kinase pathway involved in long-term potentiation and synaptic plasticity in ratsSaw, Genevieve; Krishna, Kumar ; Gupta, Neelima ; Soong, Tuck Wah ; Mallilankaraman, Karthik ; Sajikumar, Sreedharan ; Dheen, S Thameem 
101-Jan-2018Epigenetics: the panacea for cognitive decline?Sharma, Mahima ; Raghuraman, Radha; Sajikumar, Sreedharan 
112020Group III metabotropic glutamate receptors gate long-term potentiation and synaptic tagging/capture in rat hippocampal area CA2Dasgupta, A.; Lim, Y.J.; Kumar, K. ; Baby, N. ; Pang, K.L.K. ; Benoy, A.; Behnisch, T.; Sajikumar, S. 
122015Histone deacetylase 3 inhibition re-establishes synaptic tagging and capture in aging through the activation of nuclear factor kappa BSharma, M ; Shetty, M.S ; Arumugam, T.V ; Sajikumar, S 
1328-Dec-2022Hydroxychloroquine lowers Alzheimer's disease and related dementias risk and rescues molecular phenotypes related to Alzheimer's diseaseVarma, Vijay RR; Desai, Rishi JJ ; Navakkode, Sheeja ; Wong, Lik-Wei ; Anerillas, Carlos; Loeffler, Tina; Schilcher, Irene; Mahesri, Mufaddal; Chin, Kristyn; Horton, Daniel BB; Kim, Seoyoung CC; Gerhard, Tobias; Segal, Jodi BB; Schneeweiss, Sebastian; Gorospe, Myriam; Sajikumar, Sreedharan ; Thambisetty, Madhav
142015Impaired spatial memory and enhanced long-term potentiation in mice with forebrain-specific ablation of the Stim genesGarcia-Alvarez, G ; Shetty, M.S ; Lu, B ; Yap, K.A.F ; Oh-Hora, M; Sajikumar, S ; Bichler, Z ; Fivaz, M 
151-Dec-2020Inactive variants of death receptor p75(NTR) reduce Alzheimer's neuropathology by interfering with APP internalizationYI CHENJU ; GOH KET YIN ; WONG LIK WEI ; AJEENA RAMANUJAN ; KAZUHIRO TANAKA ; SAJI KUMAR SREEDHARAN ; CARLOS F. IBANEZ 
161-Sep-2021Inactive variants of death receptor p75(NTR) reduce Alzheimer's neuropathology by interfering with APP internalization (vol 40, e104450, 2021)Yi, Chenju ; Goh, Ket Yin ; Wong, Lik-Wei ; Ramanujan, Ajeena ; Tanaka, Kazuhiro ; Sajikumar, Sreedharan ; Ibanez, Carlos F 
1729-Jun-2021Inhibition of lysine methyltransferase G9a/GLP reinstates long-term synaptic plasticity and synaptic tagging/capture by facilitating protein synthesis in the hippocampal CA1 area of APP/PS1 mouse model of Alzheimer's diseaseHan, Javan Lee Tze; Pang, Karen Ka Lam ; Ang, Sheila Rui Xia; Sharma, Mahima ; Sajikumar, Sreedharan 
182015Lentiviral silencing of GSK-3β in adult dentate gyrus impairs contextual fear memory and synaptic plasticityChew B. ; Ryu J.R. ; Ng T. ; Ma D. ; Dasgupta A. ; NEO SIN HUI ; Zhao J.; Zhong Z.; Bichler Z. ; Sajikumar S. ; Goh E.L.K. 
199-Aug-2022Loss of CaV1.3 RNA editing enhances mouse hippocampal plasticity, learning, and memoryZhai, J ; Navakkode, S; Yeow, SQZ; Krishna-K, K ; Liang, MC ; Koh, JH ; Wong, RX; Yu, WP ; Sajikumar, S ; Huang, H ; Soong, TW 
2017-Oct-2019MicroRNA-134-5p inhibition rescues long-term plasticity and synaptic tagging/capture in an A beta(1-42)-induced model of Alzheimer's diseaseBaby, Nimmi ; Alagappan, Nithyakalyani; Dheen, Shaikali Thameem ; Sajikumar, Sreedharan