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Alan Prem Kumar

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Full Name
Alan Prem Kumar
Variants
Kumar, A.P.
Kumar, A.
Prem Kumar, A.
Kumar, Alan Prem Rem
 
Main Affiliation
 
Faculty
 
Email
apkumar@nus.edu.sg
 
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Publications

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Department:  DEAN'S OFFICE (MEDICINE)
Author:  Sethi G.
Policy:  Open
Type:  Article

Results 1-20 of 25 (Search time: 0.015 seconds).

Issue DateTitleAuthor(s)
11-Jul-20222,3,5,6-Tetramethylpyrazine Targets Epithelial-Mesenchymal Transition by Abrogating Manganese Superoxide Dismutase Expression and TGF beta-Driven Signaling Cascades in Colon Cancer CellsJung, Young Yun; Mohan, Chakrabhavi Dhananjaya; Eng, Huiyan; Narula, Acharan S; Namjoshi, Ojas A; Blough, Bruce E; Rangappa, Kanchugarakoppal S; Sethi, Gautam ; Kumar, Alan Prem ; Ahn, Kwang Seok
22017A novel benzimidazole derivative, MBIC inhibits tumor growth and promotes apoptosis via activation of ROS-dependent JNK signaling pathway in hepatocellular carcinomaDai X.; Wang L. ; Deivasigamni A.; Looi C.Y.; Karthikeyan C.; Trivedi P.; Chinnathambi A.; Alharbi S.A.; Arfuso F.; Dharmarajan A.; Goh B.C. ; Hui K.M. ; Kumar A.P. ; Mustafa M.R.; Sethi G. 
32018A sensitive liquid chromatography-tandem mass spectrometry method for the determination of nimbolide in mouse serum: Application to a preclinical pharmacokinetics studyWang, L ; Khoa Phan, D.-D; Syn, N; Xiang, X; Song, H; Thuya, W.L ; Yang, S ; Wong, A.L.-A ; Kumar, A.P ; Yong, W.P ; Sethi, G ; Ho, P.C.-L ; Goh, B.C 
42016ANXA1 inhibits miRNA-196a in a negative feedback loop through NF-kB and C-Myc to reduce breast cancer proliferationYuan, Y ; Anbalagan, D; Lee, L.H; Samy, R.P ; Shanmugam, M.K ; Kumar, A.P ; Sethi, G ; Lobie, P.E ; Lim, L.H.K 
52017Breast cancer stem-like cells are inhibited by diosgenin, a steroidal saponin, by the attenuation of the Wnt β-catenin signaling via the Wnt antagonist secreted frizzled related protein-4Bhuvanalakshmi, G; Basappa, Laboratory of Chemical Biology, Department of Chemistry, Bangalore University, Bangalore, India; Rangappa, K.S; Dharmarajan, A; Sethi, G ; Kumar, A.P ; Warrier, S
62018Celastrol attenuates the invasion and migration and augments the anticancer effects of bortezomib in a xenograft mouse model of multiple myelomaShanmugam, M.K ; Ahn, K.S; Lee, J.H; Kannaiyan, R; Mustafa, N ; Manu, K.A ; Siveen, K.S ; Sethi, G ; Chng, W.J ; Kumar, A.P 
72020Corilagin represses epithelial to mesenchymal transition process through modulating wnt/?-catenin signaling cascadeHwang, S.T.; Yang, M.H.; Kumar, A.P. ; Sethi, G. ; Ahn, K.S.
818-Jan-2019Cytoskeletal Proteins in Cancer and Intracellular Stress: A Therapeutic PerspectiveOng, Mei Shan; Deng, Shuo ; Halim, Clarissa Esmeralda ; Cai, Wanpei ; Tan, Tuan Zea ; Huang, Ruby Yun-Ju ; Sethi, Gautam ; Hooi, Shing Chuan ; Kumar, Alan Prem ; Yap, Celestial T 
927-Sep-2021Epigenetic derepression converts PPAR gamma into a druggable target in triple-negative and endocrine-resistant breast cancersLoo, Ser Yue; Syn, Nicholas L; Koh, Angele Pei-Fern ; Teng, Janet Cheng-Fei ; Deivasigamani, Amudha; Tan, Tuan Zea ; Thike, Aye Aye ; Vali, Shireen ; Kapoor, Shweta; Wang, Xiaoyuan ; Wang, Jiong Wei ; Tan, Puay Hoon ; Yip, George W ; Sethi, Gautam ; Huang, Ruby Yun-Ju ; Hui, Kam Man ; Wang, Lingzhi ; Goh, Boon Cher ; Kumar, Alan Prem 
1029-Jun-2016Functional characterization of selective exosite-binding inhibitors of Matrix metalloproteinase-13 (MMP-13) – experimental validation in human breast and colon cancerKodappully Siveen ; Tuan Zea Tan ; Jean-Paul Thierry ; Alan Prem Kumar ; Gautam Sethi ; Kunchithapadam Swaminathan 
112015Garcinol sensitizes human head and neck carcinoma to cisplatin in a xenograft mouse model despite downregulation of proliferative biomarkersLi F. ; Shanmugam M.K. ; Siveen K.S. ; Wang F. ; Ong T.H.; Loo S.Y. ; Swamy M.M.M.; Mandal S.; Kumar A.P. ; Goh B.C. ; Kundu T.; Ahn K.S.; Wang L.Z. ; Hui K.M. ; Sethi G. 
121-Jan-2021MicroRNA-196a promotes renal cancer cell migration and invasion by targeting BRAM1 to regulate SMAD and MAPK signaling pathwaysCui, Jianzhou ; Yuan, Yi; Shanmugam, Muthu K ; Anbalagan, Durkeshwari; Tan, Tuan Zea ; Sethi, Gautam ; Kumar, Alan Prem ; Lim, Lina HK 
132018N-substituted pyrido-1,4-Oxazin-3-ones induce apoptosis of hepatocellular carcinoma cells by targeting NF-?B signaling pathwayMohan, C.D; Bharathkumar, H; Dukanya, Department of Studies in Organic Chemistry, University of Mysore, Mysore, India; Rangappa, S; Shanmugam, M.K ; Chinnathambi, A; Alharbi, S.A; Alahmadi, T.A; Bhattacharjee, A; Lobie, P.E ; Deivasigamani, A; Hui, K.M; Sethi, G ; Basappa, Laboratory of Chemical Biology, Department of Chemistry, Bangalore University, Bangalore, India, Department of Studies in Organic Chemistry, University of Mysore, Mysore, India; Rangappa, K.S; Kumar, A.P 
142018NGAL is downregulated in oral squamous cell carcinoma and leads to increased survival, proliferation, migration and chemoresistanceMonisha J.; Roy N.K.; Padmavathi G.; Banik K.; Bordoloi D.; Khwairakpam A.D.; Arfuso F.; Chinnathambi A.; Alahmadi T.A.; Alharbi S.A.; Sethi G. ; Kumar A.P. ; Kunnumakkara A.B.
152018Novel 1,3,4-oxadiazole induces anticancer activity by targeting NF-κB in hepatocellular carcinoma cellsMohan, C.D; Anilkumar, N.C; Rangappa, S; Shanmugam, M.K ; Mishra, S ; Chinnathambi, A; Alharbi, S.A; Bhattacharjee, A; Sethi, G ; Kumar, A.P ; Basappa, Laboratory of Chemical Biology, Department of Chemistry, Bangalore University, Bangalore, India, Department of Studies in Organic Chemistry, University of Mysore, Mysore, India; Rangappa, K.S
1617-Feb-2021Plasma osteopontin as a biomarker of Alzheimer's disease and vascular cognitive impairmentChai, Yuek Ling ; Chong, Joyce R ; Raquib, Ainiah R ; Xu, Xin ; Hilal, Saima ; Venketasubramanian, Narayanaswamy; Tan, Boon Yeow ; Kumar, Alan P ; Sethi, Gautam ; Chen, Christopher P ; Lai, Mitchell KP 
17Nov-2017PPARγ Ligand-induced Annexin A1 Expression Determines Chemotherapy Response via Deubiquitination of Death Domain Kinase RIP in Triple-negative Breast Cancers.Chen, Luxi ; Yuan, Yi; Kar, Shreya; Kanchi, Madhu M ; Arora, Suruchi; Kim, Ji E; Koh, Pei F ; Yousef, Einas; Samy, Ramar P ; Shanmugam, Muthu K ; Tuan Z ; Shin, Sung W; Arfuso, Frank; Shen, Han M ; Yang, Henry; Goh, Boon C ; Park, Joo I; Gaboury, Louis; Lobie, Peter E ; Sethi, Gautam ; Lim, Lina HK ; Kumar, Alan P 
182019Stemness, pluripotentiality, and wnt antagonism: SFRP4, a wnt antagonist mediates pluripotency and stemness in glioblastomaBhuvanalakshmi, G; Gamit, N; Patil, M; Arfuso, F; Sethi, G ; Dharmarajan, A; Kumar, A.P ; Warrier, S
192014Synthesis, biological evaluation and in silico and in vitro mode-of-action analysis of novel dihydropyrimidones targeting PPAR-γBharathkumar, H; Paricharak, S; Dinesh, K.R; Siveen, K.S ; Fuchs, J.E; Rangappa, S; Mohan, C.D; Mohandas, N ; Kumar, A.P ; Sethi, G ; Bender, A; Basappa, Laboratory of Chemical Biology, Department of Chemistry, Bangalore University, Palace Road, Bangalore, 560001, India; Rangappa, K.S
202019The IκB kinase inhibitor ACHP targets the STAT3 signaling pathway in human non-small cell lung carcinoma cellsLee, J.H.; Mohan, C.D.; Basappa, S.; Rangappa, S.; Chinnathambi, A.; Alahmadi, T.A.; Alharbi, S.A.; Kumar, A.P. ; Sethi, G. ; Ahn, K.S.; Rangappa, K.S.