Please use this identifier to cite or link to this item: https://doi.org/10.1038/s41467-020-16670-2
Title: Detection of air and surface contamination by SARS-CoV-2 in hospital rooms of infected patients
Authors: Chia, P.Y.
Coleman, K.K. 
Tan, Y.K.
Ong, S.W.X.
Gum, M.
Lau, S.K.
Lim, X.F.
Lim, A.S.
Sutjipto, S.
Lee, P.H.
Son, T.T. 
Young, B.E.
Milton, D.K.
Gray, G.C. 
Schuster, S.
Barkham, T. 
De, P.P.
Vasoo, S.
Chan, M.
Ang, B.S.P.
Tan, B.H.
Leo, Y.-S. 
Ng, O.-T.
Wong, M.S.Y.
Marimuthu, K. 
Lye, D.C. 
Lim, P.L. 
Lee, C.C.
Ling, L.M.
Lee, L.
Lee, T.H.
Wong, C.S.
Sadarangani, S.
Lin, R.J.
Ng, D.H.L.
Sadasiv, M.
Yeo, T.W.
Choy, C.Y.
Tan, G.S.E.
Dimatatac, F.
Santos, I.F.
Go, C.J.
Chan, Y.K.
Tay, J.Y.
Tan, J.Y.-L.
Pandit, N.
Ho, B.C.H.
Mendis, S.
Chen, Y.Y.C.
Abdad, M.Y.
Moses, D.
for the Singapore 2019 Novel Coronavirus Outbreak Research Team.
Issue Date: 2020
Publisher: Nature Research
Citation: Chia, P.Y., Coleman, K.K., Tan, Y.K., Ong, S.W.X., Gum, M., Lau, S.K., Lim, X.F., Lim, A.S., Sutjipto, S., Lee, P.H., Son, T.T., Young, B.E., Milton, D.K., Gray, G.C., Schuster, S., Barkham, T., De, P.P., Vasoo, S., Chan, M., Ang, B.S.P., Tan, B.H., Leo, Y.-S., Ng, O.-T., Wong, M.S.Y., Marimuthu, K., Lye, D.C., Lim, P.L., Lee, C.C., Ling, L.M., Lee, L., Lee, T.H., Wong, C.S., Sadarangani, S., Lin, R.J., Ng, D.H.L., Sadasiv, M., Yeo, T.W., Choy, C.Y., Tan, G.S.E., Dimatatac, F., Santos, I.F., Go, C.J., Chan, Y.K., Tay, J.Y., Tan, J.Y.-L., Pandit, N., Ho, B.C.H., Mendis, S., Chen, Y.Y.C., Abdad, M.Y., Moses, D., for the Singapore 2019 Novel Coronavirus Outbreak Research Team. (2020). Detection of air and surface contamination by SARS-CoV-2 in hospital rooms of infected patients. Nature Communications 11 (1) : 2800. ScholarBank@NUS Repository. https://doi.org/10.1038/s41467-020-16670-2
Rights: Attribution 4.0 International
Abstract: Understanding the particle size distribution in the air and patterns of environmental contamination of SARS-CoV-2 is essential for infection prevention policies. Here we screen surface and air samples from hospital rooms of COVID-19 patients for SARS-CoV-2 RNA. Environmental sampling is conducted in three airborne infection isolation rooms (AIIRs) in the ICU and 27 AIIRs in the general ward. 245 surface samples are collected. 56.7% of rooms have at least one environmental surface contaminated. High touch surface contamination is shown in ten (66.7%) out of 15 patients in the first week of illness, and three (20%) beyond the first week of illness (p = 0.01, ?2 test). Air sampling is performed in three of the 27 AIIRs in the general ward, and detects SARS-CoV-2 PCR-positive particles of sizes >4 µm and 1–4 µm in two rooms, despite these rooms having 12 air changes per hour. This warrants further study of the airborne transmission potential of SARS-CoV-2. © 2020, The Author(s).
Source Title: Nature Communications
URI: https://scholarbank.nus.edu.sg/handle/10635/197891
ISSN: 2041-1723
DOI: 10.1038/s41467-020-16670-2
Rights: Attribution 4.0 International
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