CANCER SCIENCE INSTITUTE OF SINGAPORE

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	Issue Date	Title	Author(s)
661	23-Feb-2022	Phase Ib Dose-Finding Study of Varlitinib Combined with Weekly Paclitaxel With or Without Carboplatin +/- Trastuzumab in Advanced Solid Tumors	Lee, Matilda Xinwei; Wong, Andrea LA ; Ow, Samuel; Sundar, Raghav ; Tan, David SP ; Soo, Ross A ; Chee, Cheng Ean ; Lim, Joline SJ ; Yong, Wei Peng ; Lim, Siew Eng; Goh, Boon Cher ; Wang, Lingzhi ; Lee, Soo Chin
2	1-Aug-2003	Phase I trial of fixed dose-rate gemcitabine in combination with carboplatin in chemonaive advanced non-small-cell lung cancer: A Cancer Therapeutics Research Group study	Soo, R.A. ; Lim, H.L.; Wang, L.Z. ; Lee, H.S.; Millward, M.J.; Tok, L.T.; Lee, S.C. ; Lehnert, M.; Goh, B.C.
3	Nov-2011	Phase I and pharmacodynamic study of an orally administered novel inhibitor of histone deacetylases, SB939, in patients with refractory solid malignancies	Yong, W.P. ; Goh, B.C.; Soo, R.A. ; Toh, H.C.; Ethirajulu, K.; Wood, J.; Novotny-Diermayr, V.; Lee, S.C. ; Yeo, W.L. ; Chan, D.; Lim, D.; Seah, E.; Lim, R.; Zhu, J.
4	2015	Phase I and biomarker study of OPB-51602, a novel signal transducer and activator of transcription (STAT) 3 inhibitor, in patients with refractory solid malignancies	Wong, Andrea; Soo, Ross A.; Tan, Daniel; Lee, Soo Chin ; Lim, Joline S J; Marban, P.C.; Kong, Li Ren ; Lee, Youngjoo; Wang, Lingzhi ; Thuya, Win Lwin ; Soong, R.; Yee, M.Q.; Chin, T.M.; Cordero, Maricel Tiemsim; Asuncion, Bernadette Reyna ; Pang, B.; Pervaiz, Shazib ; Hirpara, Jayshree L. ; Sinha, Arvind; Xu, W.W.; Yuasa, M.; Tsunoda, T.; Motoyama, M.; Yamauchi, T.; Goh, Boon Cher
5	15-Jan-2013	Phase 2 trial of linifanib (ABT-869) in patients with unresectable or metastatic hepatocellular carcinoma	Toh, H.C.; Chen, P.-J.; Carr, B.I.; Knox, J.J.; Gill, S.; Ansell, P.; McKeegan, E.M.; Dowell, B.; Pedersen, M.; Qin, Q.; Qian, J.; Scappaticci, F.A.; Ricker, J.L.; Carlson, D.M.; Yong, W.P.
6	Aug-2011	Phase 2 trial of linifanib (ABT-869) in patients with advanced non-small cell lung cancer	Tan, E.-H.; Goss, G.D.; Salgia, R.; Besse, B.; Gandara, D.R.; Hanna, N.H.; Yang, J.C.-H.; Thertulien, R.; Wertheim, M.; Mazieres, J.; Hensing, T.; Lee, C.; Gupta, N.; Pradhan, R.; Qian, J.; Qin, Q.; Scappaticci, F.A.; Ricker, J.L.; Carlson, D.M.; Soo, R.A.
7	2019	Pharmacological inhibition of TFF3 enhances sensitivity of CMS4 colorectal carcinoma to 5-fluorouracil through inhibition of p44/42 MAPK	Chen, R.-M. ; Chiou, Y.-S.; Chong, Q.-Y. ; Poh, H.-M.; Tan, T.-Z. ; Zhang, M.-Y.; Ma, L.; Zhu, T.; Pandey, V.; Salundi, B.; Prem Kumar, A. ; Lobie, P.E.
8	11-Dec-2020	Pharmacological Inhibition of BAD Ser99 Phosphorylation Enhances the Efficacy of Cisplatin in Ovarian Cancer by Inhibition of Cancer Stem Cell-like Behavior	Wang, Yanxin; Chiou, Yi-Shiou; Chong, Qing-Yun ; Zhang, Mengyi; Rangappa, Kanchuragoppal S; Ma, Lan; Zhu, Tao; Kumar, Alan Prem ; Huang, Ruby Yun-Ju ; Pandey, Vijay; Basappa; Lobie, Peter E
9	1-Jan-2012	Pharmacologic synergy between dual phosphoinositide-3-kinase and mammalian target of rapamycin inhibition and 5-fluorouracil in PIK3CA mutant gastric cancer cells.	Bhattacharya, B. ; Akram, M.; Balasubramanian, I.; Tam, K.K.; Koh, K.X.; Yee, M.Q.; Soong, R.
10	1-Jan-2012	Pharmacologic synergy between dual phosphoinositide-3-kinase and mammalian target of rapamycin inhibition and 5-Fluorouracil in PIK3CA mutant gastric cancer cells	Bhattacharya, B. ; Akram, M.; Balasubramanian, I. ; Tam, K.K.Y.; Koh, K.X.; Yee, M.Q.; Soong, R.
11	Jun-2012	Pharmacologic modulation strategies to reduce dose requirements of anticancer therapy while preserving clinical efficacy	Zee, Y.-K.; Goh, B.-C.; Lee, S.-C.
12	2015	Pharmacokinetics and safety of ixazomib plus lenalidomide-dexamethasone in Asian patients with relapsed/refractory myeloma: a phase 1 study	Gupta, N; Goh, Y.T ; Min, C.-K; Lee, J.H; Kim, K; Wong, R.S.M; Chim, C.S; Hanley, M.J; Yang, H; Venkatakrishnan, K; Hui, A.-M; Esseltine, D.-L; Chng, W.J
13	Sep-2011	Pharmacokinetic modeling of plasma and intracellular concentrations of raltegravir in healthy volunteers	Wang, L. ; Soon, G.H.; Seng, K.-Y.; Li, J.; Lee, E.; Yong, E.-L.; Goh, B.-C.; Flexner, C.; Lee, L.
14	1-Jun-2022	Pharmacogenomic prediction of immune-related adverse events from immune checkpoint inhibitors among Asian patients	Huang, Yiqing; Aminkeng, Folefac ; Wong, Alvin SC; Tay, Sen Hee ; Zhao, Joseph J; Ang, Yvonne; Soo, Ross A ; Goh, Boon Cher
15	29-Nov-2018	Pharmacogenomic Prediction of Bleomycin-Induced Pneumonitis in South East Asian Hodgkin Lymphoma Patients	Lee, Joanne Shu Xian ; Poon, Li Mei; Liu, Xin; Yuen, Yi Ching; Somasundaram, Nagavalli ; Chin, Suk Teng; Teoh, Chia Meng ; Yan, Benedict; Chan, Hian Li Esther ; Chee, Yen-Lin ; Tang, Tiffany ; Farzana, Noorul; Aw, Caroline Hui Ting; Khor, Chiea Chuen ; Ngeow, Joanne Yuen Yie; Ong, Choon Kiat ; Tai, E Shyong ; Chng, Wee Joo ; Goh, Boon Cher ; Lee, Soo Chin ; Aminkeng, Folefac
16	2016	Pharmacogenetics-Guided Phase i Study of Capecitabine on an Intermittent Schedule in Patients with Advanced or Metastatic Solid Tumours	Soo, R.A ; Syn, N; Lee, S.-C; Wang, L; Lim, X.-Y; Loh, M; Tan, S.-H ; Zee, Y.-K; Wong, A.L.-A ; Chuah, B; Chan, D; Lim, S.-E; Goh, B.-C ; Soong, R ; Yong, W.-P
17	Jul-2011	Pharmacodynamic evaluation of the target efficacy of SB939, an oral HDAC inhibitor with selectivity for tumor tissue	Novotny-Diermayr, V.; Sausgruber, N.; Loh, Y.K.; Pasha, M.K.; Jayaraman, R.; Hentze, H.; Yong, W.-P. ; Goh, B.-C.; Toh, H.-C.; Ethirajulu, K.; Zhu, J.; Wood, J.M.
18	15-Feb-2009	Pharmacodynamic effects of seliciclib, an orally administered cell cycle modulator, in undifferentiated nasopharyngeal cancer	Hsieh, W.-S. ; Soo, R. ; Pen, B.-K.; Loh, T.; Dong, D.; Son, D.; Wong, L.-S.; Green, S.; Chiao, J.; Cui, C.-Y.; Lai, Y.-F.; Lee, S.-C. ; Mow, B.; Soong, R.; Salto-Tellez, M.; Goh, B.-C.
19	2006	Phagocyte-derived reactive species: salvation or suicide?	Halliwell, B.
20	6-Jul-2022	Perspectives on the Risk-Stratified Treatment of Multiple Myeloma	Davies, FE; Pawlyn, C; Usmani, SZ; San-Miguel, JF; Einsele, H; Boyle, EM; Corre, J; Auclair, D; Cho, HJ; Lonial, S; Sonneveld, P; Stewart, AK; Bergsagel, PL; Kaiser, MF; Weisel, K; Keats, JJ; Mikhael, JR; Morgan, KE; Ghobrial, IM; Orlowski, RZ; Landgren, CO; Gay, F; Caers, J; Chng, WJ ; Chari, A; Walker, BA; Kumar, SK; Costa, LJ; Anderson, KC; Morgan, GJ