Please use this identifier to cite or link to this item:
https://doi.org/10.1109/ISIC.2006.285625
| Title: | Dynamic modeling for modulation of ATP concentration at the endothelial surface by viscous shear flow | Authors: | Qin, K. Xu, Z. Zhang, H. Xiang, C. Ge, S.S. Jiang, Z. |
Keywords: | ATP Dynamic model Endothelial cells Mechanotransduction Shear stress |
Issue Date: | 2006 | Citation: | Qin, K., Xu, Z., Zhang, H., Xiang, C., Ge, S.S., Jiang, Z. (2006). Dynamic modeling for modulation of ATP concentration at the endothelial surface by viscous shear flow. IEEE International Symposium on Intelligent Control - Proceedings : 1270-1275. ScholarBank@NUS Repository. https://doi.org/10.1109/ISIC.2006.285625 | Abstract: | In this paper, dynamic modeling is investigated for shear stress induced adenosine triphosphate (ATP) release from endothelial cells (ECs). The modulation of ATP concentration at the endothelial surface by viscous shear flow is extensively investigated through numerical analysis based on the release model. The simulation results demonstrate that shear stress induced ATP release, convection and diffusion of ATP, and ATP hydrolysis by ecto-ATPase synergistically determine the ATP concentration against time at endothelium-fluid interface. © 2006 IEEE. | Source Title: | IEEE International Symposium on Intelligent Control - Proceedings | URI: | http://scholarbank.nus.edu.sg/handle/10635/51154 | ISBN: | 0780397983 | DOI: | 10.1109/ISIC.2006.285625 |
| Appears in Collections: | Staff Publications |
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