Please use this identifier to cite or link to this item: https://doi.org/10.1109/ISIC.2006.285625
Title: Dynamic modeling for modulation of ATP concentration at the endothelial surface by viscous shear flow
Authors: Qin, K.
Xu, Z.
Zhang, H.
Xiang, C. 
Ge, S.S. 
Jiang, Z.
Keywords: ATP
Dynamic model
Endothelial cells
Mechanotransduction
Shear stress
Issue Date: 2006
Source: Qin, K.,Xu, Z.,Zhang, H.,Xiang, C.,Ge, S.S.,Jiang, Z. (2006). Dynamic modeling for modulation of ATP concentration at the endothelial surface by viscous shear flow. IEEE International Symposium on Intelligent Control - Proceedings : 1270-1275. ScholarBank@NUS Repository. https://doi.org/10.1109/ISIC.2006.285625
Abstract: In this paper, dynamic modeling is investigated for shear stress induced adenosine triphosphate (ATP) release from endothelial cells (ECs). The modulation of ATP concentration at the endothelial surface by viscous shear flow is extensively investigated through numerical analysis based on the release model. The simulation results demonstrate that shear stress induced ATP release, convection and diffusion of ATP, and ATP hydrolysis by ecto-ATPase synergistically determine the ATP concentration against time at endothelium-fluid interface. © 2006 IEEE.
Source Title: IEEE International Symposium on Intelligent Control - Proceedings
URI: http://scholarbank.nus.edu.sg/handle/10635/51154
ISBN: 0780397983
DOI: 10.1109/ISIC.2006.285625
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