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https://doi.org/10.1007/s10237-007-0088-8
| Title: | Dynamic modeling for shear stress induced ATP release from vascular endothelial cells | Authors: | Qin, K.R. Xiang, C. Xu, Z. Cao, L.L. Ge, S.S. Jiang, Z.L. |
Keywords: | ATP Calcium dynamics Dynamic model Endothelial cells Mechanotransduction Shear stress Static model |
Issue Date: | Oct-2008 | Citation: | Qin, K.R., Xiang, C., Xu, Z., Cao, L.L., Ge, S.S., Jiang, Z.L. (2008-10). Dynamic modeling for shear stress induced ATP release from vascular endothelial cells. Biomechanics and Modeling in Mechanobiology 7 (5) : 345-353. ScholarBank@NUS Repository. https://doi.org/10.1007/s10237-007-0088-8 | Abstract: | A dynamic model is proposed for shear stress induced adenosine triphosphate (ATP) release from endothelial cells (ECs). The dynamic behavior of the ATP/ADP concentration at the endothelial surface by viscous shear flow is investigated through simulation studies based on the dynamic ATP release model. The numerical results demonstrate that the ATP/ADP concentration against time at endothelium-fluid interface predicted by the dynamic ATP release model is more consistent with the experimental observations than that predicted by previous static ATP release model. © 2007 Springer-Verlag. | Source Title: | Biomechanics and Modeling in Mechanobiology | URI: | http://scholarbank.nus.edu.sg/handle/10635/50902 | ISSN: | 16177959 | DOI: | 10.1007/s10237-007-0088-8 |
| Appears in Collections: | Staff Publications |
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