Please use this identifier to cite or link to this item: https://doi.org/10.1007/s10237-007-0088-8
Title: Dynamic modeling for shear stress induced ATP release from vascular endothelial cells
Authors: Qin, K.R.
Xiang, C. 
Xu, Z.
Cao, L.L.
Ge, S.S. 
Jiang, Z.L.
Keywords: ATP
Calcium dynamics
Dynamic model
Endothelial cells
Mechanotransduction
Shear stress
Static model
Issue Date: Oct-2008
Source: Qin, K.R., Xiang, C., Xu, Z., Cao, L.L., Ge, S.S., Jiang, Z.L. (2008-10). Dynamic modeling for shear stress induced ATP release from vascular endothelial cells. Biomechanics and Modeling in Mechanobiology 7 (5) : 345-353. ScholarBank@NUS Repository. https://doi.org/10.1007/s10237-007-0088-8
Abstract: A dynamic model is proposed for shear stress induced adenosine triphosphate (ATP) release from endothelial cells (ECs). The dynamic behavior of the ATP/ADP concentration at the endothelial surface by viscous shear flow is investigated through simulation studies based on the dynamic ATP release model. The numerical results demonstrate that the ATP/ADP concentration against time at endothelium-fluid interface predicted by the dynamic ATP release model is more consistent with the experimental observations than that predicted by previous static ATP release model. © 2007 Springer-Verlag.
Source Title: Biomechanics and Modeling in Mechanobiology
URI: http://scholarbank.nus.edu.sg/handle/10635/50902
ISSN: 16177959
DOI: 10.1007/s10237-007-0088-8
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