Please use this identifier to cite or link to this item:
|Title:||pFlexAna: detecting conformational changes in remotely related proteins.||Authors:||Nigham, A.
|Issue Date:||2008||Citation:||Nigham, A., Tucker-Kellogg, L., Mihalek, I., Verma, C., Hsu, D. (2008). pFlexAna: detecting conformational changes in remotely related proteins.. Nucleic acids research 36 (Web Server issue) : W246-251. ScholarBank@NUS Repository. https://doi.org/10.1093/nar/gkn259||Abstract:||The pFlexAna (protein flexibility analyzer) web server detects and displays conformational changes in remotely related proteins, without relying on sequence homology. To do so, it first applies a reliable statistical test to align core protein fragments that are structurally similar and then clusters these aligned fragment pairs into 'super-alignments', according to the similarity of geometric transformations that align them. The result is that the dominant conformational changes occur between the clusters, while the smaller conformational changes occur within a cluster. pFlexAna is available at http://bigbird.comp.nus.edu.sg/pfa2/.||Source Title:||Nucleic acids research||URI:||http://scholarbank.nus.edu.sg/handle/10635/43089||ISSN:||13624962||DOI:||10.1093/nar/gkn259|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Jul 3, 2020
checked on Jun 29, 2020
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.