Please use this identifier to cite or link to this item:
https://doi.org/10.1093/nar/gkn259
| DC Field | Value | |
|---|---|---|
| dc.title | pFlexAna: detecting conformational changes in remotely related proteins. | |
| dc.contributor.author | Nigham, A. | |
| dc.contributor.author | Tucker-Kellogg, L. | |
| dc.contributor.author | Mihalek, I. | |
| dc.contributor.author | Verma, C. | |
| dc.contributor.author | Hsu, D. | |
| dc.date.accessioned | 2013-07-23T09:24:40Z | |
| dc.date.available | 2013-07-23T09:24:40Z | |
| dc.date.issued | 2008 | |
| dc.identifier.citation | Nigham, A., Tucker-Kellogg, L., Mihalek, I., Verma, C., Hsu, D. (2008). pFlexAna: detecting conformational changes in remotely related proteins.. Nucleic acids research 36 (Web Server issue) : W246-251. ScholarBank@NUS Repository. https://doi.org/10.1093/nar/gkn259 | |
| dc.identifier.issn | 13624962 | |
| dc.identifier.uri | http://scholarbank.nus.edu.sg/handle/10635/43089 | |
| dc.description.abstract | The pFlexAna (protein flexibility analyzer) web server detects and displays conformational changes in remotely related proteins, without relying on sequence homology. To do so, it first applies a reliable statistical test to align core protein fragments that are structurally similar and then clusters these aligned fragment pairs into 'super-alignments', according to the similarity of geometric transformations that align them. The result is that the dominant conformational changes occur between the clusters, while the smaller conformational changes occur within a cluster. pFlexAna is available at http://bigbird.comp.nus.edu.sg/pfa2/. | |
| dc.description.uri | http://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1093/nar/gkn259 | |
| dc.source | Scopus | |
| dc.type | Article | |
| dc.contributor.department | COMPUTER SCIENCE | |
| dc.contributor.department | BIOLOGICAL SCIENCES | |
| dc.description.doi | 10.1093/nar/gkn259 | |
| dc.description.sourcetitle | Nucleic acids research | |
| dc.description.volume | 36 | |
| dc.description.issue | Web Server issue | |
| dc.description.page | W246-251 | |
| dc.identifier.isiut | 000258142300046 | |
| Appears in Collections: | Staff Publications | |
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