Please use this identifier to cite or link to this item:
Title: Are 3D printed resin surgical splints safe to use in the mouth? A comparative in vitro study
Authors: Sha, Y
Quah, B 
Sng, TJH 
Yong, CW 
Islam, I 
Wong, RCW 
Issue Date: 1-Feb-2023
Publisher: Elsevier BV
Citation: Sha, Y, Quah, B, Sng, TJH, Yong, CW, Islam, I, Wong, RCW (2023-02-01). Are 3D printed resin surgical splints safe to use in the mouth? A comparative in vitro study. Annals of 3D Printed Medicine 9 : 100097-100097. ScholarBank@NUS Repository.
Abstract: Introduction: In orthognathic surgery, surgical splints made of polymethymethacrylate or its variants are used to position the jaws before osteofixation, and occasionally left in-situ for a short duration to guide the occlusion postoperatively. However, allergic reactions can be caused by unreacted dental resin (monomers). Computer aided design/Computer Aided Manufacturing (CADCAM) surgical splints are now more commonly used than the conventionally “handmade” splints. It is unclear if these splints contain uncured residual monomers in any detectable quantity. Materials and methods: CADCAM surgical splints were made from 2 commonly used resins and compared with splints made manually with autopolymerising resin. The splints were immersed in saline at 37°C for 2 weeks to simulate use in the mouth, and the contents were analysed for uncured resin leaching with High Power Liquid Chromatography (HPLC) at different time intervals. Results: Uncured resin content was higher in the conventionally made splint (15,246µg/L on Day 1, 13,539 µg/L on Day 7, and 6,203µg/L on Day 14). One of the CADCAM resins had undetectable monomer quantities, while the other CADCAM resin demonstrated significantly less free monomer compared to the autopolymerising resin (382 µg/L on Day 1, 179 µg/L on Day 7 and 65.2 µg/L on Day 14). Conclusion: CADCAM surgical splints have much lower free monomer content compared to the conventionally made splint, and are safe for clinical use.
Source Title: Annals of 3D Printed Medicine
ISSN: 2666-9641
DOI: 10.1016/j.stlm.2022.100097
Appears in Collections:Elements
Staff Publications

Show full item record
Files in This Item:
File Description SizeFormatAccess SettingsVersion 
1-s2.0-S2666964122000510-main.pdfPublished version1.17 MBAdobe PDF



Page view(s)

checked on Jun 8, 2023


checked on Jun 8, 2023

Google ScholarTM



Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.