Please use this identifier to cite or link to this item: https://doi.org/10.1364/boe.412156
Title: OCT-GAN: Single step shadow and noise removal from optical coherence tomography images of the human optic nerve head
Authors: CHEONG, H. A. R. I. S.
DEVALLA, S. R. I. P. A. D. K. R. I. S. H. N. A.
CHUANGSUWANICH, T. H. A. N. A. D. E. T. 
TUN, T. I. N. A.
WANG, X. I. A. O. F. E. I.
AUNG, T. I. N. 
SCHMETTERER, L. E. O. P. O. L. D. 
BUIST, M. A. R. T. I. N. L. 
BOOTE, C. R. A. I. G.
Thiéry, A.H. 
GIRARD, M. I. C. H. A. E. L. J. A. 
Issue Date: 19-Feb-2021
Publisher: The Optical Society
Citation: CHEONG, H. A. R. I. S., DEVALLA, S. R. I. P. A. D. K. R. I. S. H. N. A., CHUANGSUWANICH, T. H. A. N. A. D. E. T., TUN, T. I. N. A., WANG, X. I. A. O. F. E. I., AUNG, T. I. N., SCHMETTERER, L. E. O. P. O. L. D., BUIST, M. A. R. T. I. N. L., BOOTE, C. R. A. I. G., Thiéry, A.H., GIRARD, M. I. C. H. A. E. L. J. A. (2021-02-19). OCT-GAN: Single step shadow and noise removal from optical coherence tomography images of the human optic nerve head. Biomedical Optics Express 12 (3) : 1482-1498. ScholarBank@NUS Repository. https://doi.org/10.1364/boe.412156
Rights: Attribution 4.0 International
Abstract: Speckle noise and retinal shadows within OCT B-scans occlude important edges, fine textures and deep tissues, preventing accurate and robust diagnosis by algorithms and clinicians. We developed a single process that successfully removed both noise and retinal shadows from unseen single-frame B-scans within 10.4ms. Mean average gradient magnitude (AGM) for the proposed algorithm was 57.2% higher than current state-of-the-art, while mean peak signal to noise ratio (PSNR), contrast to noise ratio (CNR), and structural similarity index metric (SSIM) increased by 11.1%, 154% and 187% respectively compared to single-frame B-scans. Mean intralayer contrast (ILC) improvement for the retinal nerve fiber layer (RNFL), photoreceptor layer (PR) and retinal pigment epithelium (RPE) layers decreased from 0.362 plusmn; 0.133 to 0.142 ± 0.102, 0.449 ± 0.116 to 0.0904 ± 0.0769, 0.381 ± 0.100 to 0.0590 ± 0.0451 respectively. The proposed algorithm reduces the necessity for long image acquisition times, minimizes expensive hardware requirements and reduces motion artifacts in OCT images. © 2021 Optical Society of America under the terms of the OSA Open Access Publishing Agreement.
Source Title: Biomedical Optics Express
URI: https://scholarbank.nus.edu.sg/handle/10635/232132
ISSN: 2156-7085
DOI: 10.1364/boe.412156
Rights: Attribution 4.0 International
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