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dc.titleOCT-GAN: Single step shadow and noise removal from optical coherence tomography images of the human optic nerve head
dc.contributor.authorCHEONG, H. A. R. I. S.
dc.contributor.authorDEVALLA, S. R. I. P. A. D. K. R. I. S. H. N. A.
dc.contributor.authorCHUANGSUWANICH, T. H. A. N. A. D. E. T.
dc.contributor.authorTUN, T. I. N. A.
dc.contributor.authorWANG, X. I. A. O. F. E. I.
dc.contributor.authorAUNG, T. I. N.
dc.contributor.authorSCHMETTERER, L. E. O. P. O. L. D.
dc.contributor.authorBUIST, M. A. R. T. I. N. L.
dc.contributor.authorBOOTE, C. R. A. I. G.
dc.contributor.authorThiéry, A.H.
dc.contributor.authorGIRARD, M. I. C. H. A. E. L. J. A.
dc.identifier.citationCHEONG, H. A. R. I. S., DEVALLA, S. R. I. P. A. D. K. R. I. S. H. N. A., CHUANGSUWANICH, T. H. A. N. A. D. E. T., TUN, T. I. N. A., WANG, X. I. A. O. F. E. I., AUNG, T. I. N., SCHMETTERER, L. E. O. P. O. L. D., BUIST, M. A. R. T. I. N. L., BOOTE, C. R. A. I. G., Thiéry, A.H., GIRARD, M. I. C. H. A. E. L. J. A. (2021-02-19). OCT-GAN: Single step shadow and noise removal from optical coherence tomography images of the human optic nerve head. Biomedical Optics Express 12 (3) : 1482-1498. ScholarBank@NUS Repository.
dc.description.abstractSpeckle noise and retinal shadows within OCT B-scans occlude important edges, fine textures and deep tissues, preventing accurate and robust diagnosis by algorithms and clinicians. We developed a single process that successfully removed both noise and retinal shadows from unseen single-frame B-scans within 10.4ms. Mean average gradient magnitude (AGM) for the proposed algorithm was 57.2% higher than current state-of-the-art, while mean peak signal to noise ratio (PSNR), contrast to noise ratio (CNR), and structural similarity index metric (SSIM) increased by 11.1%, 154% and 187% respectively compared to single-frame B-scans. Mean intralayer contrast (ILC) improvement for the retinal nerve fiber layer (RNFL), photoreceptor layer (PR) and retinal pigment epithelium (RPE) layers decreased from 0.362 plusmn; 0.133 to 0.142 ± 0.102, 0.449 ± 0.116 to 0.0904 ± 0.0769, 0.381 ± 0.100 to 0.0590 ± 0.0451 respectively. The proposed algorithm reduces the necessity for long image acquisition times, minimizes expensive hardware requirements and reduces motion artifacts in OCT images. © 2021 Optical Society of America under the terms of the OSA Open Access Publishing Agreement.
dc.publisherThe Optical Society
dc.rightsAttribution 4.0 International
dc.sourceScopus OA2021
dc.contributor.departmentDEPT OF BIOMEDICAL ENGINEERING
dc.contributor.departmentDUKE-NUS MEDICAL SCHOOL
dc.contributor.departmentDEAN'S OFFICE (COLLEGE OF DESIGN & ENG)
dc.contributor.departmentDUKE-NUS OFFICE OF ACAD & CLINICAL DEVT
dc.description.sourcetitleBiomedical Optics Express
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