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https://doi.org/10.1016/j.tips.2020.04.007
| Title: | Therapeutic RNA Strategies for Chronic Obstructive Pulmonary Disease | Authors: | Mei, Dan Tan, WS Daniel Tay, Yvonne Mukhopadhyay, Amartya Wong, WS Fred |
Keywords: | Science & Technology Life Sciences & Biomedicine Pharmacology & Pharmacy ANTISENSE OLIGONUCLEOTIDES IN-VIVO COPD INFLAMMATION DELIVERY PATHOGENESIS PROTECTS VERSICAN SMOKERS ASTHMA |
Issue Date: | 1-Jul-2020 | Publisher: | ELSEVIER SCIENCE LONDON | Citation: | Mei, Dan, Tan, WS Daniel, Tay, Yvonne, Mukhopadhyay, Amartya, Wong, WS Fred (2020-07-01). Therapeutic RNA Strategies for Chronic Obstructive Pulmonary Disease. TRENDS IN PHARMACOLOGICAL SCIENCES 41 (7) : 475-486. ScholarBank@NUS Repository. https://doi.org/10.1016/j.tips.2020.04.007 | Abstract: | Chronic obstructive pulmonary disease (COPD) is characterized by airflow limitation with persistent respiratory symptoms. Current therapeutics for COPD are largely borrowed from the drug armamentarium for the treatment of asthma, which has different pathophysiological mechanisms from COPD. COPD has been linked to dysregulated expression of mRNAs and noncoding (nc)RNAs including miRNAs, PIWI-interacting (pi)RNAs, long noncoding (lnc)RNAs, and circular (circ)RNAs. This review highlights and discusses some recent advances towards development of RNA therapeutics for COPD. | Source Title: | TRENDS IN PHARMACOLOGICAL SCIENCES | URI: | https://scholarbank.nus.edu.sg/handle/10635/229051 | ISSN: | 01656147 18733735 |
DOI: | 10.1016/j.tips.2020.04.007 |
| Appears in Collections: | Staff Publications Elements |
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| File | Description | Size | Format | Access Settings | Version | |
|---|---|---|---|---|---|---|
| RNA COPD TIPS Printed Paper.pdf | 1.74 MB | Adobe PDF | CLOSED | None |
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