Please use this identifier to cite or link to this item: https://doi.org/10.1097/APO.0000000000000275
Title: Cataract surgery and the 6-year incidence of age-related macular degeneration in a multiethnic asian cohort
Authors: Gan, A.T.L.
Man, R.E.K. 
Cheung, C.M.G. 
Kumari, N.
Fenwick, E.K.
Sabanayagam, C. 
Tham, Y.-C.
Tan, N.Y.Q.
Mitchell, P.
Wong, T.Y. 
Cheng, C.-Y. 
Lamoureux, E.L. 
Keywords: age-related macular degeneration
Asian and elderly population
cataract surgery
Issue Date: 2020
Publisher: Lippincott Williams and Wilkins
Citation: Gan, A.T.L., Man, R.E.K., Cheung, C.M.G., Kumari, N., Fenwick, E.K., Sabanayagam, C., Tham, Y.-C., Tan, N.Y.Q., Mitchell, P., Wong, T.Y., Cheng, C.-Y., Lamoureux, E.L. (2020). Cataract surgery and the 6-year incidence of age-related macular degeneration in a multiethnic asian cohort. Asia-Pacific Journal of Ophthalmology 9 (2) : 130-136. ScholarBank@NUS Repository. https://doi.org/10.1097/APO.0000000000000275
Rights: Attribution-NonCommercial-NoDerivatives 4.0 International
Abstract: Purpose:The aim of this study was to determine whether cataract surgery was associated with age-related macular degeneration (AMD) development in Asian patients.Design:Longitudinal cohort study.Methods:Participants from the Singapore Malay and Indian Eye Studies were recruited between 2004 and 2015. A total of 6790 late-AMD-free eyes from 3475 individuals were followed for 6 years on average. Multivariable regression analysis using generalized estimating equations determined associations between cataract surgery and the incidence of any, early, and late AMD.Results:The mean age (SD) of participants was 55.5 (9.1) years; 48.1% were male; 11.3% of eyes had cataract surgery recorded; incident any, early, and late AMD developed in 238 (3.6%), 222 (3.4%), and 29 (0.4%) eyes, respectively. Operated eyes had higher incidence of late AMD [1.4% vs 0.3%; adjusted risk ratio (RR): 3.47, 95% confidence interval (CI) 1.40-8.57], but not early AMD (6.0% vs 3.0%, adjusted RR: 1.12, 95% CI 0.76-1.64) or any AMD (6.9 vs 3.2%, adjusted RR: 1.23, 95% CI 0.85-1.78).Conclusions:Our data are consistent with findings in population-based Caucasian studies that cataract surgery may be associated with incidence of late AMD. However, the absolute risk of late AMD development remains low and physicians should continue to balance the benefits and risks of cataract surgery in elderly patients. © 2020 Asia-Pacific Academy of Ophthalmology. All rights reserved.
Source Title: Asia-Pacific Journal of Ophthalmology
URI: https://scholarbank.nus.edu.sg/handle/10635/197820
ISSN: 21620989
DOI: 10.1097/APO.0000000000000275
Rights: Attribution-NonCommercial-NoDerivatives 4.0 International
Appears in Collections:Staff Publications
Elements

Show full item record
Files in This Item:
File Description SizeFormatAccess SettingsVersion 
10_1097_APO_0000000000000275.pdf265.86 kBAdobe PDF

OPEN

NoneView/Download

SCOPUSTM   
Citations

1
checked on Nov 29, 2021

Page view(s)

38
checked on Dec 2, 2021

Google ScholarTM

Check

Altmetric


This item is licensed under a Creative Commons License Creative Commons