Please use this identifier to cite or link to this item: https://doi.org/10.3389/fphys.2018.01181
Title: Normal values of myocardial deformation assessed by cardiovascular magnetic resonance feature tracking in a healthy Chinese population: A multicenter study
Authors: Peng, J
Zhao, X
Zhao, L
Fan, Z
Wang, Z
Chen, H
Leng, S
Allen, J 
Tan, R.-S 
Koh, A.S 
Ma, X
Lou, M
Zhong, L 
Keywords: age
aged
article
cardiovascular magnetic resonance
Chinese
controlled study
female
heart left atrium
heart left ventricle
heart right ventricle
human
human experiment
infant
major clinical study
male
multicenter study
normal value
Issue Date: 2018
Citation: Peng, J, Zhao, X, Zhao, L, Fan, Z, Wang, Z, Chen, H, Leng, S, Allen, J, Tan, R.-S, Koh, A.S, Ma, X, Lou, M, Zhong, L (2018). Normal values of myocardial deformation assessed by cardiovascular magnetic resonance feature tracking in a healthy Chinese population: A multicenter study. Frontiers in Physiology 9 (SEP) : 1181. ScholarBank@NUS Repository. https://doi.org/10.3389/fphys.2018.01181
Abstract: Reference values on atrial and ventricular strain from cardiovascular magnetic resonance (CMR) are essential in identifying patients with impaired atrial and ventricular function. However, reference values have not been established for Chinese subjects. One hundred and fifty healthy volunteers (75 Males/75 Females; 18-82 years) were recruited. All underwent CMR scans with images acceptable for further strain analysis. Subjects were stratified by age: Group 1, 18-44 years; Group 2, 45-59 years; Group 3, =60 years. Feature tracking of CMR cine imaging was used to obtain left atrial global longitudinal (LA Ell) and circumferential strains (LA Ecc) and respective systolic strain rates, left ventricular longitudinal (LV Ell), circumferential (LV Ecc) and radial strains (LV Err) and their respective strain rates, and right ventricular longitudinal strain (RV Ell) and strain rate. LA Ell and LA Ecc were 32.8 ± 9.2% and 40.3 ± 13.4%, respectively, and RV Ell was -29.3 ± 6.0%. LV Ell, LV Ecc and LV Err were -22.4 ± 2.9%, -24.3 ± 3.1%, and 79.0 ± 19.4%, respectively. LV Ell and LV Ecc were higher in females than males (P < 0.05). LA Ell, LA Ecc, and LV Ecc decreased, while LV Err increased with age (P < 0.05). LV Ell and RV Ell were not shown to be associated with age. Normal ranges for atrial and ventricular strain and strain rates are provided using CMR feature tracking in Chinese subjects. © 2018 Peng, Zhao, Zhao, Fan, Wang, Chen, Leng, Allen, Tan, Koh, Ma, Lou and Zhong.
Source Title: Frontiers in Physiology
URI: https://scholarbank.nus.edu.sg/handle/10635/175368
ISSN: 1664-042X
DOI: 10.3389/fphys.2018.01181
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