Please use this identifier to cite or link to this item: https://doi.org/10.1038/s41598-017-16634-5
Title: Unraveling the molecular mechanism of photosynthetic toxicity of highly fluorescent silver nanoclusters to Scenedesmus obliquus
Authors: Zhang, L
Goswami, N 
Xie, J 
Zhang, B
He, Y 
Keywords: chlorophyll
metal nanoparticle
silver
drug effect
fluorescence
gene expression profiling
gene expression regulation
genetics
metabolism
photosynthesis
reproducibility
Scenedesmus
ultrastructure
ultraviolet spectrophotometry
Chlorophyll
Fluorescence
Gene Expression Profiling
Gene Expression Regulation
Metabolic Networks and Pathways
Metal Nanoparticles
Photosynthesis
Reproducibility of Results
Scenedesmus
Silver
Spectrophotometry, Ultraviolet
Issue Date: 2017
Citation: Zhang, L, Goswami, N, Xie, J, Zhang, B, He, Y (2017). Unraveling the molecular mechanism of photosynthetic toxicity of highly fluorescent silver nanoclusters to Scenedesmus obliquus. Scientific Reports 7 (1) : 16432. ScholarBank@NUS Repository. https://doi.org/10.1038/s41598-017-16634-5
Abstract: While the discovery of numerous attractive properties of silver at the nanoscale has increased their demand in many sectors including medicine, optics, sensing, painting and cosmetics, it has also raised wide public concerns about their effect on living organisms in aquatic environment. Despite the continuous effort to understand the various aspects of the toxicity of silver nanomaterials, the molecular level understanding on their cytotoxicity mechanism to biological organisms has remained unclear. Herein, we demonstrated the underlying mechanism of the photosynthetic toxicity against green algae namely, Scenedesmus obliquus by using an emerging silver nanomaterial, called silver nanoclusters (defined as r-Ag NCs). By exploiting the unique fluorescence properties of r-Ag NCs along with various other analytical/biological tools, we proposed that the photosynthetic toxicity of r-Ag NCs was largely attributed to the "joint-Toxicity" effect of particulate form of r-Ag NCs and its released Ag+, which resulted in the disruption of the electron transport chain of light reaction and affected the content of key enzymes (RuBP carboxylase/ oxygenase) of Calvin cycle of algae cells. We believe that the present study can also be applied to the assessment of the ecological risk derived from other metal nanoparticles. © 2017 The Author(s).
Source Title: Scientific Reports
URI: https://scholarbank.nus.edu.sg/handle/10635/175092
ISSN: 20452322
DOI: 10.1038/s41598-017-16634-5
Appears in Collections:Elements
Staff Publications

Show full item record
Files in This Item:
File Description SizeFormatAccess SettingsVersion 
10_1038_s41598-017-16634-5.pdf3.56 MBAdobe PDF

OPEN

NoneView/Download

SCOPUSTM   
Citations

17
checked on Nov 23, 2022

Page view(s)

188
checked on Nov 24, 2022

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.