Please use this identifier to cite or link to this item: https://doi.org/10.1007/s12576-016-0472-1
Title: A new method of infrared thermography for quantification of brown adipose tissue activation in healthy adults (TACTICAL): a randomized trial
Authors: Ang, Q.Y
Goh, H.J
Cao, Y
Li, Y
Chan, S.-P 
Swain, J.L 
Henry, C.J 
Leow, M.K.-S 
Keywords: fluorodeoxyglucose f 18
adult
brown adipose tissue
controlled study
double blind procedure
energy metabolism
human
infrared spectrophotometry
male
normal human
obesity
oxidation reduction reaction
pathophysiology
physiology
procedures
prospective study
randomized controlled trial
skin temperature
thermogenesis
thermography
young adult
Adipose Tissue, Brown
Adult
Double-Blind Method
Energy Metabolism
Fluorodeoxyglucose F18
Healthy Volunteers
Humans
Male
Obesity
Oxidation-Reduction
Prospective Studies
Skin Temperature
Spectrophotometry, Infrared
Thermogenesis
Thermography
Young Adult
Issue Date: 2017
Citation: Ang, Q.Y, Goh, H.J, Cao, Y, Li, Y, Chan, S.-P, Swain, J.L, Henry, C.J, Leow, M.K.-S (2017). A new method of infrared thermography for quantification of brown adipose tissue activation in healthy adults (TACTICAL): a randomized trial. Journal of Physiological Sciences 67 (3) : 395-406. ScholarBank@NUS Repository. https://doi.org/10.1007/s12576-016-0472-1
Abstract: The ability to alter the amount and activity of brown adipose tissue (BAT) in human adults is a potential strategy to manage obesity and related metabolic disorders associated with food, drug, and environmental stimuli with BAT activating/recruiting capacity. Infrared thermography (IRT) provides a non-invasive and inexpensive alternative to the current methods (e.g. 18F-FDG PET) used to assess BAT. We have quantified BAT activation in the cervical-supraclavicular (C-SCV) region using IRT video imaging and a novel image computational algorithm by studying C-SCV heat production in healthy young men after cold stimulation and the ingestion of capsinoids in a prospective double-blind placebo-controlled randomized trial. Subjects were divided into low-BAT and high-BAT groups based on changes in IR emissions in the C-SCV region induced by cold. The high-BAT group showed significant increases in energy expenditure, fat oxidation, and heat output in the C-SCV region post-capsinoid ingestion compared to post-placebo ingestion, but the low-BAT group did not. Based on these results, we conclude that IRT is a promising tool for quantifying BAT activity. © 2016, The Author(s).
Source Title: Journal of Physiological Sciences
URI: https://scholarbank.nus.edu.sg/handle/10635/173789
ISSN: 18806546
DOI: 10.1007/s12576-016-0472-1
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