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Title: Solid phase synthesis of pyridazine derivatives using polymer-bound sodium benzenesulfinate
Authors: Chen, Y. 
Lam, Y. 
Lee, S.-Y. 
Issue Date: 2001
Citation: Chen, Y.,Lam, Y.,Lee, S.-Y. (2001). Solid phase synthesis of pyridazine derivatives using polymer-bound sodium benzenesulfinate. Chemistry Letters (3) : 274-275. ScholarBank@NUS Repository.
Abstract: A new solid phase synthesis of 3,6-disubstituted pyridazine derivatives, resulting from the reaction of polymer-bound sodium benzenesulfinate with α-bromoketone substrates followed by condensation with hydrazine, is described. Mild basic conditions for the condensation reaction simultaneously release the desired product from the solid support. The crystal structure of 3,6-bis(p-chlorophenyl)pyridazine is reported.
Source Title: Chemistry Letters
ISSN: 03667022
Appears in Collections:Staff Publications

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