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|Title:||Solid phase synthesis of pyridazine derivatives using polymer-bound sodium benzenesulfinate|
|Authors:||Chen, Y. |
|Source:||Chen, Y.,Lam, Y.,Lee, S.-Y. (2001). Solid phase synthesis of pyridazine derivatives using polymer-bound sodium benzenesulfinate. Chemistry Letters (3) : 274-275. ScholarBank@NUS Repository.|
|Abstract:||A new solid phase synthesis of 3,6-disubstituted pyridazine derivatives, resulting from the reaction of polymer-bound sodium benzenesulfinate with α-bromoketone substrates followed by condensation with hydrazine, is described. Mild basic conditions for the condensation reaction simultaneously release the desired product from the solid support. The crystal structure of 3,6-bis(p-chlorophenyl)pyridazine is reported.|
|Source Title:||Chemistry Letters|
|Appears in Collections:||Staff Publications|
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