Please use this identifier to cite or link to this item: https://doi.org/10.1039/c2cc33476c
Title: Microarray-guided discovery of two-photon (2P) small molecule probes for live-cell imaging of cysteinyl cathepsin activities
Authors: Na, Z.
Li, L. 
Uttamchandani, M. 
Yao, S.Q. 
Issue Date: 25-Jul-2012
Citation: Na, Z., Li, L., Uttamchandani, M., Yao, S.Q. (2012-07-25). Microarray-guided discovery of two-photon (2P) small molecule probes for live-cell imaging of cysteinyl cathepsin activities. Chemical Communications 48 (58) : 7304-7306. ScholarBank@NUS Repository. https://doi.org/10.1039/c2cc33476c
Abstract: A microarray immobilized with 105 aldehyde-containing small molecules was screened against mammalian cell lysates over-expressing cathepsin L to identify two potent inhibitors, which were subsequently converted into cell-permeable probes capable of live-cell imaging of endogenous cysteinyl cathepsin activities by two-photon fluorescence microscopy. © 2012 The Royal Society of Chemistry.
Source Title: Chemical Communications
URI: http://scholarbank.nus.edu.sg/handle/10635/76489
ISSN: 13597345
DOI: 10.1039/c2cc33476c
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

17
checked on Dec 5, 2019

WEB OF SCIENCETM
Citations

18
checked on Dec 5, 2019

Page view(s)

87
checked on Dec 1, 2019

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.