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Please use this identifier to cite or link to this item: https://doi.org/10.1039/c2cc33476c
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dc.titleMicroarray-guided discovery of two-photon (2P) small molecule probes for live-cell imaging of cysteinyl cathepsin activities
dc.contributor.authorNa, Z.
dc.contributor.authorLi, L.
dc.contributor.authorUttamchandani, M.
dc.contributor.authorYao, S.Q.
dc.date.accessioned2014-06-23T05:43:25Z
dc.date.available2014-06-23T05:43:25Z
dc.date.issued2012-07-25
dc.identifier.citationNa, Z., Li, L., Uttamchandani, M., Yao, S.Q. (2012-07-25). Microarray-guided discovery of two-photon (2P) small molecule probes for live-cell imaging of cysteinyl cathepsin activities. Chemical Communications 48 (58) : 7304-7306. ScholarBank@NUS Repository. https://doi.org/10.1039/c2cc33476c
dc.identifier.issn13597345
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/76489
dc.description.abstractA microarray immobilized with 105 aldehyde-containing small molecules was screened against mammalian cell lysates over-expressing cathepsin L to identify two potent inhibitors, which were subsequently converted into cell-permeable probes capable of live-cell imaging of endogenous cysteinyl cathepsin activities by two-photon fluorescence microscopy. © 2012 The Royal Society of Chemistry.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1039/c2cc33476c
dc.sourceScopus
dc.typeArticle
dc.contributor.departmentCHEMISTRY
dc.description.doi10.1039/c2cc33476c
dc.description.sourcetitleChemical Communications
dc.description.volume48
dc.description.issue58
dc.description.page7304-7306
dc.description.codenCHCOF
dc.identifier.isiut000305624500024
Appears in Collections:Staff Publications

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