Please use this identifier to cite or link to this item:
https://doi.org/10.1039/c2cc33476c
| Title: | Microarray-guided discovery of two-photon (2P) small molecule probes for live-cell imaging of cysteinyl cathepsin activities | Authors: | Na, Z. Li, L. Uttamchandani, M. Yao, S.Q. |
Issue Date: | 25-Jul-2012 | Citation: | Na, Z., Li, L., Uttamchandani, M., Yao, S.Q. (2012-07-25). Microarray-guided discovery of two-photon (2P) small molecule probes for live-cell imaging of cysteinyl cathepsin activities. Chemical Communications 48 (58) : 7304-7306. ScholarBank@NUS Repository. https://doi.org/10.1039/c2cc33476c | Abstract: | A microarray immobilized with 105 aldehyde-containing small molecules was screened against mammalian cell lysates over-expressing cathepsin L to identify two potent inhibitors, which were subsequently converted into cell-permeable probes capable of live-cell imaging of endogenous cysteinyl cathepsin activities by two-photon fluorescence microscopy. © 2012 The Royal Society of Chemistry. | Source Title: | Chemical Communications | URI: | http://scholarbank.nus.edu.sg/handle/10635/76489 | ISSN: | 13597345 | DOI: | 10.1039/c2cc33476c |
| Appears in Collections: | Staff Publications |
Show full item record
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.