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https://doi.org/10.1039/c3cc42187b
Title: | Highly diastereoselective and enantioselective direct Michael addition of phthalide derivatives to nitroolefins | Authors: | Luo, J. Wang, H. Zhong, F. Kwiatkowski, J. Xu, L.-W. Lu, Y. |
Issue Date: | 28-Jun-2013 | Citation: | Luo, J., Wang, H., Zhong, F., Kwiatkowski, J., Xu, L.-W., Lu, Y. (2013-06-28). Highly diastereoselective and enantioselective direct Michael addition of phthalide derivatives to nitroolefins. Chemical Communications 49 (51) : 5775-5777. ScholarBank@NUS Repository. https://doi.org/10.1039/c3cc42187b | Abstract: | The first asymmetric Michael addition of 3-substituted phthalides to nitroolefins promoted by amino acid-incorporating multifunctional catalysts has been developed. The reported method led to the synthesis of 3,3-disubstituted phthalide derivatives in high yields, and in a highly diastereoselective and enantioselective manner. Facile synthesis of a chiral bicyclic lactam has also been demonstrated. © 2013 The Royal Society of Chemistry. | Source Title: | Chemical Communications | URI: | http://scholarbank.nus.edu.sg/handle/10635/76298 | ISSN: | 13597345 | DOI: | 10.1039/c3cc42187b |
Appears in Collections: | Staff Publications |
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