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|Title:||Highly diastereoselective and enantioselective direct Michael addition of phthalide derivatives to nitroolefins|
|Source:||Luo, J., Wang, H., Zhong, F., Kwiatkowski, J., Xu, L.-W., Lu, Y. (2013-06-28). Highly diastereoselective and enantioselective direct Michael addition of phthalide derivatives to nitroolefins. Chemical Communications 49 (51) : 5775-5777. ScholarBank@NUS Repository. https://doi.org/10.1039/c3cc42187b|
|Abstract:||The first asymmetric Michael addition of 3-substituted phthalides to nitroolefins promoted by amino acid-incorporating multifunctional catalysts has been developed. The reported method led to the synthesis of 3,3-disubstituted phthalide derivatives in high yields, and in a highly diastereoselective and enantioselective manner. Facile synthesis of a chiral bicyclic lactam has also been demonstrated. © 2013 The Royal Society of Chemistry.|
|Source Title:||Chemical Communications|
|Appears in Collections:||Staff Publications|
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