Please use this identifier to cite or link to this item:
https://doi.org/10.1002/chem.201003761
| Title: | Fluorinated aromatic ketones as nucleophiles in the asymmetric organocatalytic formation of C-C and C-N bonds: A facile route to the construction of fluorinated quaternary stereogenic centers | Authors: | Zhao, Y. Pan, Y. Liu, H. Yang, Y. Jiang, Z. Tan, C.-H. |
Keywords: | amination fluorine Mannich reaction organocatalysis quaternary stereogenic center |
Issue Date: | 21-Mar-2011 | Citation: | Zhao, Y., Pan, Y., Liu, H., Yang, Y., Jiang, Z., Tan, C.-H. (2011-03-21). Fluorinated aromatic ketones as nucleophiles in the asymmetric organocatalytic formation of C-C and C-N bonds: A facile route to the construction of fluorinated quaternary stereogenic centers. Chemistry - A European Journal 17 (13) : 3571-3574. ScholarBank@NUS Repository. https://doi.org/10.1002/chem.201003761 | Abstract: | Highly enantioselective Mannich and α-amination reactions have been successfully developed using α-fluorinated aromatic ketones as fluorocarbon nucleophiles in the presence of a bicyclic chiral guanidine (see scheme; Ms=methanesulfonyl). This method is a simple and efficient approach to the construction of fluorinated quaternary stereogenic centers. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. | Source Title: | Chemistry - A European Journal | URI: | http://scholarbank.nus.edu.sg/handle/10635/76199 | ISSN: | 09476539 | DOI: | 10.1002/chem.201003761 |
| Appears in Collections: | Staff Publications |
Show full item record
Files in This Item:
There are no files associated with this item.
SCOPUSTM
Citations
46
checked on Dec 14, 2019
WEB OF SCIENCETM
Citations
46
checked on Dec 6, 2019
Page view(s)
56
checked on Dec 1, 2019
Google ScholarTM
Check
Altmetric
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.