C3-Spacer-containing circular oligonucleotides as inhibitors of human topoisomerase I

Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.bmcl.2008.04.076

Title:	C3-Spacer-containing circular oligonucleotides as inhibitors of human topoisomerase I
Authors:	Wang, Y. Ng, M.T.T. Zhou, T. Li, X. Tan, C.H. Li, T.
Keywords:	Circular oligonucleotide Enzyme inhibitor Human topoisomerase I
Issue Date:	15-Jun-2008
Citation:	Wang, Y., Ng, M.T.T., Zhou, T., Li, X., Tan, C.H., Li, T. (2008-06-15). C3-Spacer-containing circular oligonucleotides as inhibitors of human topoisomerase I. Bioorganic and Medicinal Chemistry Letters 18 (12) : 3597-3602. ScholarBank@NUS Repository. https://doi.org/10.1016/j.bmcl.2008.04.076
Abstract:	Some dumbbell-shaped circular oligonucleotides containing internal C3-spacers and Topo I-binding sites were designed and synthesized which displayed high inhibitory efficiency on the activity of human Topo I as well as resisted the degradation by some DNA repair enzymes. © 2008 Elsevier Ltd. All rights reserved.
Source Title:	Bioorganic and Medicinal Chemistry Letters
URI:	http://scholarbank.nus.edu.sg/handle/10635/75686
ISSN:	0960894X
DOI:	10.1016/j.bmcl.2008.04.076
Appears in Collections:	Staff Publications

There are no files associated with this item.

Check