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|Title:||C3-Spacer-containing circular oligonucleotides as inhibitors of human topoisomerase I|
Human topoisomerase I
|Citation:||Wang, Y., Ng, M.T.T., Zhou, T., Li, X., Tan, C.H., Li, T. (2008-06-15). C3-Spacer-containing circular oligonucleotides as inhibitors of human topoisomerase I. Bioorganic and Medicinal Chemistry Letters 18 (12) : 3597-3602. ScholarBank@NUS Repository. https://doi.org/10.1016/j.bmcl.2008.04.076|
|Abstract:||Some dumbbell-shaped circular oligonucleotides containing internal C3-spacers and Topo I-binding sites were designed and synthesized which displayed high inhibitory efficiency on the activity of human Topo I as well as resisted the degradation by some DNA repair enzymes. © 2008 Elsevier Ltd. All rights reserved.|
|Source Title:||Bioorganic and Medicinal Chemistry Letters|
|Appears in Collections:||Staff Publications|
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