Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.bmcl.2008.04.076
Title: C3-Spacer-containing circular oligonucleotides as inhibitors of human topoisomerase I
Authors: Wang, Y.
Ng, M.T.T.
Zhou, T.
Li, X.
Tan, C.H. 
Li, T. 
Keywords: Circular oligonucleotide
Enzyme inhibitor
Human topoisomerase I
Issue Date: 15-Jun-2008
Citation: Wang, Y., Ng, M.T.T., Zhou, T., Li, X., Tan, C.H., Li, T. (2008-06-15). C3-Spacer-containing circular oligonucleotides as inhibitors of human topoisomerase I. Bioorganic and Medicinal Chemistry Letters 18 (12) : 3597-3602. ScholarBank@NUS Repository. https://doi.org/10.1016/j.bmcl.2008.04.076
Abstract: Some dumbbell-shaped circular oligonucleotides containing internal C3-spacers and Topo I-binding sites were designed and synthesized which displayed high inhibitory efficiency on the activity of human Topo I as well as resisted the degradation by some DNA repair enzymes. © 2008 Elsevier Ltd. All rights reserved.
Source Title: Bioorganic and Medicinal Chemistry Letters
URI: http://scholarbank.nus.edu.sg/handle/10635/75686
ISSN: 0960894X
DOI: 10.1016/j.bmcl.2008.04.076
Appears in Collections:Staff Publications

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