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https://doi.org/10.1039/c2cc31587d
| Title: | Bicyclic guanidine-catalyzed asymmetric Michael additions of 3-benzyl-substituted oxindoles to N-maleimides | Authors: | Li, L. Chen, W. Yang, W. Pan, Y. Liu, H. Tan, C.-H. Jiang, Z. |
Issue Date: | 25-May-2012 | Citation: | Li, L., Chen, W., Yang, W., Pan, Y., Liu, H., Tan, C.-H., Jiang, Z. (2012-05-25). Bicyclic guanidine-catalyzed asymmetric Michael additions of 3-benzyl-substituted oxindoles to N-maleimides. Chemical Communications 48 (42) : 5124-5126. ScholarBank@NUS Repository. https://doi.org/10.1039/c2cc31587d | Abstract: | A bicyclic guanidine-catalyzed Michael addition of 3-benzyl substituted oxindoles to N-maleimides has been developed to produce oxindole derivatives with a quaternary carbon chiral center at the 3-position in excellent yields and enantio- and diastereoselectivities. This is the first incorporation of N-benzylic α-branched succinimides into 3,3-disubstituted oxindoles. © 2012 The Royal Society of Chemistry. | Source Title: | Chemical Communications | URI: | http://scholarbank.nus.edu.sg/handle/10635/75652 | ISSN: | 13597345 | DOI: | 10.1039/c2cc31587d |
| Appears in Collections: | Staff Publications |
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