Please use this identifier to cite or link to this item: https://doi.org/10.1039/c2cc31587d
Title: Bicyclic guanidine-catalyzed asymmetric Michael additions of 3-benzyl-substituted oxindoles to N-maleimides
Authors: Li, L.
Chen, W.
Yang, W.
Pan, Y.
Liu, H.
Tan, C.-H. 
Jiang, Z.
Issue Date: 25-May-2012
Citation: Li, L., Chen, W., Yang, W., Pan, Y., Liu, H., Tan, C.-H., Jiang, Z. (2012-05-25). Bicyclic guanidine-catalyzed asymmetric Michael additions of 3-benzyl-substituted oxindoles to N-maleimides. Chemical Communications 48 (42) : 5124-5126. ScholarBank@NUS Repository. https://doi.org/10.1039/c2cc31587d
Abstract: A bicyclic guanidine-catalyzed Michael addition of 3-benzyl substituted oxindoles to N-maleimides has been developed to produce oxindole derivatives with a quaternary carbon chiral center at the 3-position in excellent yields and enantio- and diastereoselectivities. This is the first incorporation of N-benzylic α-branched succinimides into 3,3-disubstituted oxindoles. © 2012 The Royal Society of Chemistry.
Source Title: Chemical Communications
URI: http://scholarbank.nus.edu.sg/handle/10635/75652
ISSN: 13597345
DOI: 10.1039/c2cc31587d
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