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|Title:||Bicyclic guanidine-catalyzed asymmetric Michael additions of 3-benzyl-substituted oxindoles to N-maleimides|
|Citation:||Li, L., Chen, W., Yang, W., Pan, Y., Liu, H., Tan, C.-H., Jiang, Z. (2012-05-25). Bicyclic guanidine-catalyzed asymmetric Michael additions of 3-benzyl-substituted oxindoles to N-maleimides. Chemical Communications 48 (42) : 5124-5126. ScholarBank@NUS Repository. https://doi.org/10.1039/c2cc31587d|
|Abstract:||A bicyclic guanidine-catalyzed Michael addition of 3-benzyl substituted oxindoles to N-maleimides has been developed to produce oxindole derivatives with a quaternary carbon chiral center at the 3-position in excellent yields and enantio- and diastereoselectivities. This is the first incorporation of N-benzylic α-branched succinimides into 3,3-disubstituted oxindoles. © 2012 The Royal Society of Chemistry.|
|Source Title:||Chemical Communications|
|Appears in Collections:||Staff Publications|
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