Please use this identifier to cite or link to this item:
https://doi.org/10.1002/anie.201205940
| Title: | A switchable two-photon membrane tracer capable of imaging membrane-associated protein tyrosine phosphatase activities | Authors: | Li, L. Shen, X. Xu, Q.-H. Yao, S.Q. |
Keywords: | Bioimaging Fluorescence microscopy Membrane proteins Phosphatases Small-molecule probes |
Issue Date: | 2-Jan-2013 | Citation: | Li, L., Shen, X., Xu, Q.-H., Yao, S.Q. (2013-01-02). A switchable two-photon membrane tracer capable of imaging membrane-associated protein tyrosine phosphatase activities. Angewandte Chemie - International Edition 52 (1) : 424-428. ScholarBank@NUS Repository. https://doi.org/10.1002/anie.201205940 | Abstract: | When I look into your cells: A two-photon dye (Flu7) was developed (see scheme), which strongly fluoresces only upon selective binding to the plasma membrane of mammalian cells. Upon addition of a UV- and phosphatase-controlled quencher (Q12), the system exhibits ON/OFF/ON fluorescence switching and can be used to image membrane-associated receptor-like protein tyrosine phosphatase (RPTP) activity. © 2013 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim. | Source Title: | Angewandte Chemie - International Edition | URI: | http://scholarbank.nus.edu.sg/handle/10635/75494 | ISSN: | 14337851 | DOI: | 10.1002/anie.201205940 |
| Appears in Collections: | Staff Publications |
Show full item record
Files in This Item:
There are no files associated with this item.
SCOPUSTM
Citations
60
checked on Dec 9, 2019
WEB OF SCIENCETM
Citations
61
checked on Dec 9, 2019
Page view(s)
76
checked on Dec 15, 2019
Google ScholarTM
Check
Altmetric
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.