Please use this identifier to cite or link to this item:
https://doi.org/10.1101/2021.09.20.21263808
| Title: | Human Milk Antibodies Elicited by BNT162b2 Vaccination have reduced activity against SARS-CoV-2 Variants of Concern | Authors: | Low, Jia Ming Gu, Yue Ng, Melissa Shu Feng Wang, Liang Wei Amin, Zubair Zhong, Youjia MacAry, Paul |
Issue Date: | 2021 | Citation: | Low, Jia Ming, Gu, Yue, Ng, Melissa Shu Feng, Wang, Liang Wei, Amin, Zubair, Zhong, Youjia, MacAry, Paul (2021). Human Milk Antibodies Elicited by BNT162b2 Vaccination have reduced activity against SARS-CoV-2 Variants of Concern. ScholarBank@NUS Repository. https://doi.org/10.1101/2021.09.20.21263808 | Abstract: | We detected the presence of SARS-CoV-2 specific IgA against all major VOCs in milk out to 6 weeks after D2 of BNT162b2. These likely confer some protection to the breastfed infants, who are ineligible for vaccination and are at risk of severe COVID-19. However, we detected significantly reduced milk IgA binding to VOCs, including the globally dominant Delta variant, suggesting reduced protection for breastfeeding infants. Additionally, these antibodies were significantly reduced by as early as 4-6 weeks after D2. | URI: | https://scholarbank.nus.edu.sg/handle/10635/239499 | DOI: | 10.1101/2021.09.20.21263808 |
| Appears in Collections: | Elements Staff Publications |
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| Human Milk Antibodies Elicited by BNT162b2 Vaccination have reduced activity against SARS-CoV-2 Variants of Concern.pdf | 203.81 kB | Adobe PDF | OPEN | Pre-print | View/Download |
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