Please use this identifier to cite or link to this item: https://doi.org/10.32604/biocell.2023.025357
Title: Magnetic mitohormesis: A non-invasive therapy for inflammatory disorders?
Authors: Franco-Obreg, Alfredo 
Keywords: Science & Technology
Life Sciences & Biomedicine
Biology
Life Sciences & Biomedicine - Other Topics
ROS
Pulsed electromagnetic fields
Mitochondria
Myokines
Inflammation
SKELETAL-MUSCLE
MITOCHONDRIAL DYSFUNCTION
SYNERGIZE
NETWORK
FIELDS
HEALTH
Issue Date: 2-Nov-2022
Publisher: TECH SCIENCE PRESS
Citation: Franco-Obreg, Alfredo (2022-11-02). Magnetic mitohormesis: A non-invasive therapy for inflammatory disorders?. BIOCELL 47 (2). ScholarBank@NUS Repository. https://doi.org/10.32604/biocell.2023.025357
Abstract: An organism's survival depends on its ability to adapt to stress. Mitochondria are the cellular integrators of environmental stressors that ultimately translate their responses at the organismal level, and are thus central to the process whereby organisms adapt to their respective environments. Mitochondria produce molecular energy via oxidative phosphorylation that then allows cells to biosynthetically respond and adapt to changes in their environment. Reactive oxygen species (ROS) are by-products of oxidative phosphorylation that can be either beneficial or damaging, depending on the context; ROS are hence both the conveyors of environmental stress as well as cellular “adaptogens”. Mitohormesis refers to the process whereby low levels of oxidative stress spur survival adaptations, whereas excessive levels stymie survival. Low energy and frequency pulsing electromagnetic fields have been recently shown capable of stimulating mitochondrial respiration and ROS production and instilling mitohormetic survival adaptations, similarly to, yet independently of, exercise, opening avenues for the future development of Magnetic Mitohormetic interventions for the improvement of human health. This viewpoint explores the possibilities and nuances of magnetic-based therapies as a form of clinical intervention to non-invasively activate magnetic mitohormesis for the management of chronic diseases.
Source Title: BIOCELL
URI: https://scholarbank.nus.edu.sg/handle/10635/236237
ISSN: 0327-9545
1667-5746
DOI: 10.32604/biocell.2023.025357
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