Please use this identifier to cite or link to this item: https://doi.org/10.1007/s00421-019-04101-0
Title: Sensitivity and reliability of cerebral oxygenation responses to postural changes measured with near-infrared spectroscopy
Authors: Mol, Arjen
Woltering, Jeffrey HH
Colier, Willy NJM
Maier, Andrea B 
Meskers, Carel GM
van Wezel, Richard JA
Keywords: Science & Technology
Life Sciences & Biomedicine
Physiology
Sport Sciences
Cerebrovascular circulation
Sensitivity
Reliability
Orthostatic hypotension
Cerebral autoregulation
ORTHOSTATIC HYPOTENSION
TISSUE OXYGENATION
HEMODYNAMIC-RESPONSES
ARTERIAL-PRESSURE
HEAD-UP
AUTOREGULATION
MONITOR
AREA
Issue Date: 1-May-2019
Publisher: SPRINGER
Citation: Mol, Arjen, Woltering, Jeffrey HH, Colier, Willy NJM, Maier, Andrea B, Meskers, Carel GM, van Wezel, Richard JA (2019-05-01). Sensitivity and reliability of cerebral oxygenation responses to postural changes measured with near-infrared spectroscopy. EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY 119 (5) : 1117-1125. ScholarBank@NUS Repository. https://doi.org/10.1007/s00421-019-04101-0
Abstract: Purpose: Cerebral oxygenation as measured by near-infrared spectroscopy (NIRS) might be useful to discriminate between physiological and pathological responses after standing up in individuals with orthostatic hypotension. This study addressed the physiological sensitivity of the cerebral oxygenation responses as measured by NIRS to different types and speeds of postural changes in healthy adults and assessed the reliability of these responses. Methods: Cerebral oxygenated hemoglobin (O 2 Hb), deoxygenated hemoglobin (HHb) and tissue saturation index (TSI) were measured bilaterally on the forehead of 15 healthy individuals (12 male, age range 18–27) using NIRS. Participants performed three repeats of sit to stand, and slow and rapid supine to stand movements. Responses were defined as the difference between mean, minimum and maximum O 2 Hb, HHb and TSI values after standing up and baseline. Test–retest, interobserver and intersensor reliabilities were addressed using intraclass correlation coefficients (ICCs). Results: The minimum O 2 Hb response was most sensitive to postural changes and showed significant differences (− 4.09 µmol/L, p < 0.001) between standing up from sitting and supine position, but not between standing up at different speeds (− 0.31 µmol/L, p = 0.70). The minimum O 2 Hb response was the most reliable parameter (ICC > 0.6). Conclusions: In healthy individuals, NIRS-based cerebral oxygenation parameters are sensitive to postural change and discriminate between standing up from supine and sitting position with minimum O 2 Hb response as the most sensitive and reliable parameter. The results underpin the potential value for future clinical use of NIRS in individuals with orthostatic hypotension.
Source Title: EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
URI: https://scholarbank.nus.edu.sg/handle/10635/234986
ISSN: 1439-6319
1439-6327
DOI: 10.1007/s00421-019-04101-0
Appears in Collections:Elements
Staff Publications

Show full item record
Files in This Item:
File Description SizeFormatAccess SettingsVersion 
Sensitivity and reliability of cerebral oxygenation responses to postural changes measured with near-infrared spectroscopy.pdf811.74 kBAdobe PDF

OPEN

PublishedView/Download

SCOPUSTM   
Citations

22
checked on Feb 3, 2023

Page view(s)

19
checked on Feb 2, 2023

Download(s)

1
checked on Feb 2, 2023

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.