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Title: Prevalence and Associated Factors of Sarcopenia in Singaporean Adults—The Yishun Study
Authors: Pang, Benedict Wei Jun
Wee, Shiou-Liang 
Lau, Lay Khoon
Jabbar, Khalid Abdul
Seah, Wei Ting
Ng, Daniella Hui Min
Ling Tan, Q.L.
Chen, Kenneth Kexun
Jagadish, Mallya Ullal
Ng, Tze Pin 
Keywords: Muscle strength
skeletal muscle mass
Issue Date: 1-Apr-2021
Publisher: Elsevier Inc.
Citation: Pang, Benedict Wei Jun, Wee, Shiou-Liang, Lau, Lay Khoon, Jabbar, Khalid Abdul, Seah, Wei Ting, Ng, Daniella Hui Min, Ling Tan, Q.L., Chen, Kenneth Kexun, Jagadish, Mallya Ullal, Ng, Tze Pin (2021-04-01). Prevalence and Associated Factors of Sarcopenia in Singaporean Adults—The Yishun Study. Journal of the American Medical Directors Association 22 (4) : 8850-8850000000000. ScholarBank@NUS Repository.
Rights: Attribution-NonCommercial-NoDerivatives 4.0 International
Abstract: Objectives: To describe the normative values of sarcopenia among community-dwelling adults (?21 years of age); compare the prevalence of sarcopenia using Asian Working Group for Sarcopenia criteria, 2014 (AWGS2014), Asian Working Group for Sarcopenia criteria, 2019 (AWGS2019), and European Working Group on Sarcopenia in Older People criteria, 2018 (EWGSOP2) guidelines; and identify factors associated with sarcopenia. Design: Participants were recruited through random sampling. Sarcopenia assessments were performed using a dual-energy x-ray absorptiometry scan (muscle mass), handgrip test (muscle strength), and usual walking test (physical performance). Questionnaires were administered to evaluate lifestyle and cognition. Setting and Participants: In total, 542 community-dwelling Singaporeans were recruited (21?90 years old, 57.9% women). Methods: We assessed anthropometry, body composition, and questionnaire-based physical and cognitive factors, and estimated sarcopenia prevalence according to the AWGS2014, AWGS2019, and EWGSOP2 recommendations, and examined associations using logistic regression. Results: According to AWGS2019, the Singapore population-adjusted sarcopenia prevalence was 13.6% (men 13.0%; women 14.2%) overall, and 32.2% (men 33.7%, women 30.9%) in those aged 60 years and above. The cut-offs derived from young adult reference group for low appendicular lean mass index were 5.28 kg/m2 for men and 3.69 kg/m2 for women (lower than AWGS recommended cut-off); for gait speed it was 0.82 m/s, (AWGS2019 recommended cut-off 1.0 m/s, AWGS2014 cut-off was 0.8 m/s); and for handgrip strength it was 27.9 kg/m2 for men and 16.7 kg/m2 for women (close to AWGS2019 recommendation). Age, sex, marital status, alcoholism, physical activity, body mass index, waist circumference, and global cognition were associated with sarcopenia (P < .05). Conclusions and Implications: This is the first study to provide reference values of muscle mass, strength, and gait speed across the adult lifespan of Singaporeans. Using AWGS2019 criteria, sarcopenia is prominent in older age (32.2% in ?60 years old), but it is already nontrivial (6.9%) among young and middle-age persons. Multidomain lifestyle modifications addressing muscle strength, cognition, and nutrition over the adult lifespan are important to delay the development of sarcopenia. © 2020 AMDA – The Society for Post-Acute and Long-Term Care Medicine
Source Title: Journal of the American Medical Directors Association
ISSN: 1525-8610
DOI: 10.1016/j.jamda.2020.05.029
Rights: Attribution-NonCommercial-NoDerivatives 4.0 International
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