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Title: Fructus lycii: A natural dietary supplement for amelioration of retinal diseases
Authors: Neelam, Kumari 
Dey, Sonali
Sim, Ralene
Lee, Jason
Au Eong, K.-G. 
Keywords: Age-related macular degeneration
Diabetic retinopathy
Fructus lycii
Retinitis pigmentosa
Issue Date: 16-Jan-2021
Publisher: MDPI AG
Citation: Neelam, Kumari, Dey, Sonali, Sim, Ralene, Lee, Jason, Au Eong, K.-G. (2021-01-16). Fructus lycii: A natural dietary supplement for amelioration of retinal diseases. Nutrients 13 (1) : Jan-25. ScholarBank@NUS Repository.
Rights: Attribution 4.0 International
Abstract: Fructus lycii (F. lycii) is an exotic “berry-type” fruit of the plant Lycium barbarum that is characterized by a complex mixture of bioactive compounds distinguished by their high antioxidant potential. F. lycii is used in traditional Chinese home cooking and in the Chinese Pharmacopeia as an aid to vision and longevity as well as a remedy for diabetes to balance “yin” and “yang” in the body for about two centuries. Although a myriad of bioactive compounds have been isolated from F. lycii, polysaccharides, carotenoids, flavonoids, and phenolics represent the key functional components of F. lycii. F. lycii has been shown to exhibit a wide range of biological activities in experimental settings including antioxidant, anti-inflammatory, antiapoptotic, and neuroprotective effects. Despite its medicinal role dating back to the eighteenth century in the Far East and robust evidence of beneficial effects on ocular health and retinal diseases originating mainly from studies in animal models, the role of F. lycii in the clinical management of retinal diseases is yet to be established. This article comprehensively reviews the literature germane to F. lycii and retinal diseases with particular emphasis on age-related macular degeneration, diabetic retinopathy, and retinitis pigmentosa, which are commonly seen in clinical practice. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.
Source Title: Nutrients
ISSN: 2072-6643
DOI: 10.3390/nu13010246
Rights: Attribution 4.0 International
Appears in Collections:Staff Publications

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