Please use this identifier to cite or link to this item: https://doi.org/10.3390/nu13010246
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dc.titleFructus lycii: A natural dietary supplement for amelioration of retinal diseases
dc.contributor.authorNeelam, Kumari
dc.contributor.authorDey, Sonali
dc.contributor.authorSim, Ralene
dc.contributor.authorLee, Jason
dc.contributor.authorAu Eong, K.-G.
dc.date.accessioned2022-10-11T08:05:41Z
dc.date.available2022-10-11T08:05:41Z
dc.date.issued2021-01-16
dc.identifier.citationNeelam, Kumari, Dey, Sonali, Sim, Ralene, Lee, Jason, Au Eong, K.-G. (2021-01-16). Fructus lycii: A natural dietary supplement for amelioration of retinal diseases. Nutrients 13 (1) : Jan-25. ScholarBank@NUS Repository. https://doi.org/10.3390/nu13010246
dc.identifier.issn2072-6643
dc.identifier.urihttps://scholarbank.nus.edu.sg/handle/10635/232176
dc.description.abstractFructus lycii (F. lycii) is an exotic “berry-type” fruit of the plant Lycium barbarum that is characterized by a complex mixture of bioactive compounds distinguished by their high antioxidant potential. F. lycii is used in traditional Chinese home cooking and in the Chinese Pharmacopeia as an aid to vision and longevity as well as a remedy for diabetes to balance “yin” and “yang” in the body for about two centuries. Although a myriad of bioactive compounds have been isolated from F. lycii, polysaccharides, carotenoids, flavonoids, and phenolics represent the key functional components of F. lycii. F. lycii has been shown to exhibit a wide range of biological activities in experimental settings including antioxidant, anti-inflammatory, antiapoptotic, and neuroprotective effects. Despite its medicinal role dating back to the eighteenth century in the Far East and robust evidence of beneficial effects on ocular health and retinal diseases originating mainly from studies in animal models, the role of F. lycii in the clinical management of retinal diseases is yet to be established. This article comprehensively reviews the literature germane to F. lycii and retinal diseases with particular emphasis on age-related macular degeneration, diabetic retinopathy, and retinitis pigmentosa, which are commonly seen in clinical practice. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.
dc.publisherMDPI AG
dc.rightsAttribution 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.sourceScopus OA2021
dc.subjectAge-related macular degeneration
dc.subjectAntioxidants
dc.subjectCarotenoids
dc.subjectDiabetic retinopathy
dc.subjectFructus lycii
dc.subjectRetinitis pigmentosa
dc.typeReview
dc.contributor.departmentDEAN'S OFFICE (DUKE-NUS MEDICAL SCHOOL)
dc.contributor.departmentDEPT OF OPHTHALMOLOGY
dc.description.doi10.3390/nu13010246
dc.description.sourcetitleNutrients
dc.description.volume13
dc.description.issue1
dc.description.pageJan-25
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