Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.pacs.2022.100377
Title: Biochemical “decoding” of breast ultrasound images with optoacoustic tomography fusion: First-in-human display of lipid and collagen signals on breast ultrasound
Authors: Goh, Y 
Balasundaram, G
Tan, HM
Putti, TC 
Tang, SW 
Ng, CWQ 
Buhari, SA 
Fang, E
Moothanchery, M
Bi, R
Olivo, M 
Quek, ST 
Keywords: Breast
Collagen
Lipid
Optoacoustic
Tomography
Issue Date: 1-Sep-2022
Publisher: Elsevier BV
Citation: Goh, Y, Balasundaram, G, Tan, HM, Putti, TC, Tang, SW, Ng, CWQ, Buhari, SA, Fang, E, Moothanchery, M, Bi, R, Olivo, M, Quek, ST (2022-09-01). Biochemical “decoding” of breast ultrasound images with optoacoustic tomography fusion: First-in-human display of lipid and collagen signals on breast ultrasound. Photoacoustics 27 : 100377-. ScholarBank@NUS Repository. https://doi.org/10.1016/j.pacs.2022.100377
Abstract: To date, studies which utilized ultrasound (US) and optoacoustic tomography (OT) fusion (US-OT) in biochemical differentiation of malignant and benign breast conditions have relied on limited biochemical data such as oxyhaemoglobin (OH) and deoxyhaemoglobin (DH) only. There has been no data of the largest biochemical components of breast fibroglandular tissue: lipid and collagen. Here, the authors believe the ability to image collagen and lipids within the breast tissue could serve as an important milestone in breast US-OT imaging with many potential downstream clinical applications. Hence, we would like to present the first-in-human US-OT demonstration of lipid and collagen differentiation in an excised breast tissue from a 38-year-old female.
Source Title: Photoacoustics
URI: https://scholarbank.nus.edu.sg/handle/10635/229818
ISSN: 22135979
DOI: 10.1016/j.pacs.2022.100377
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