Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.pacs.2022.100377
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dc.titleBiochemical “decoding” of breast ultrasound images with optoacoustic tomography fusion: First-in-human display of lipid and collagen signals on breast ultrasound
dc.contributor.authorGoh, Y
dc.contributor.authorBalasundaram, G
dc.contributor.authorTan, HM
dc.contributor.authorPutti, TC
dc.contributor.authorTang, SW
dc.contributor.authorNg, CWQ
dc.contributor.authorBuhari, SA
dc.contributor.authorFang, E
dc.contributor.authorMoothanchery, M
dc.contributor.authorBi, R
dc.contributor.authorOlivo, M
dc.contributor.authorQuek, ST
dc.date.accessioned2022-08-02T08:37:39Z
dc.date.available2022-08-02T08:37:39Z
dc.date.issued2022-09-01
dc.identifier.citationGoh, Y, Balasundaram, G, Tan, HM, Putti, TC, Tang, SW, Ng, CWQ, Buhari, SA, Fang, E, Moothanchery, M, Bi, R, Olivo, M, Quek, ST (2022-09-01). Biochemical “decoding” of breast ultrasound images with optoacoustic tomography fusion: First-in-human display of lipid and collagen signals on breast ultrasound. Photoacoustics 27 : 100377-. ScholarBank@NUS Repository. https://doi.org/10.1016/j.pacs.2022.100377
dc.identifier.issn22135979
dc.identifier.urihttps://scholarbank.nus.edu.sg/handle/10635/229818
dc.description.abstractTo date, studies which utilized ultrasound (US) and optoacoustic tomography (OT) fusion (US-OT) in biochemical differentiation of malignant and benign breast conditions have relied on limited biochemical data such as oxyhaemoglobin (OH) and deoxyhaemoglobin (DH) only. There has been no data of the largest biochemical components of breast fibroglandular tissue: lipid and collagen. Here, the authors believe the ability to image collagen and lipids within the breast tissue could serve as an important milestone in breast US-OT imaging with many potential downstream clinical applications. Hence, we would like to present the first-in-human US-OT demonstration of lipid and collagen differentiation in an excised breast tissue from a 38-year-old female.
dc.publisherElsevier BV
dc.sourceElements
dc.subjectBreast
dc.subjectCollagen
dc.subjectLipid
dc.subjectOptoacoustic
dc.subjectTomography
dc.typeArticle
dc.date.updated2022-07-25T00:28:07Z
dc.contributor.departmentDEPT OF DIAGNOSTIC RADIOLOGY
dc.contributor.departmentDEPT OF PATHOLOGY
dc.contributor.departmentDEPT OF PHARMACY
dc.contributor.departmentDEPT OF SURGERY
dc.description.doi10.1016/j.pacs.2022.100377
dc.description.sourcetitlePhotoacoustics
dc.description.volume27
dc.description.page100377-
dc.published.stateUnpublished
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