Please use this identifier to cite or link to this item: https://doi.org/10.29026/oea.2022.210045
Title: Confocal laser speckle autocorrelation imaging of dynamic flow in microvasculature
Authors: Du, E
Shen, Shuhao 
Qiu, Anqi 
Chen, Nanguang 
Keywords: laser speckle
autocorrelation
confocal
line scan
flow
Issue Date: 1-Jan-2022
Publisher: Opto-Electronic Advances
Citation: Du, E, Shen, Shuhao, Qiu, Anqi, Chen, Nanguang (2022-01-01). Confocal laser speckle autocorrelation imaging of dynamic flow in microvasculature. Opto-Electronic Advances 5 (2) : 210045-210045. ScholarBank@NUS Repository. https://doi.org/10.29026/oea.2022.210045
Abstract: Laser speckle imaging has been widely used for in-vivo visualization of blood perfusion in biological tissues. However, existing laser speckle imaging techniques suffer from limited quantification accuracy and spatial resolution. Here we re-port a novel design and implementation of a powerful laser speckle imaging platform to solve the two critical limitations. The core technique of our platform is a combination of line scan confocal microscopy with laser speckle autocorrelation imaging, which is termed Line Scan Laser Speckle Autocorrelation Imaging (LS-LSAI). The technical advantages of LS-LSAI include high spatial resolution (~4.4 μm) for visualizing and quantifying blood flow in microvessels, as well as video-rate imaging speed for tracing dynamic flow.
Source Title: Opto-Electronic Advances
URI: https://scholarbank.nus.edu.sg/handle/10635/226833
ISSN: 2096-4579
DOI: 10.29026/oea.2022.210045
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